SCHEMBL206197

SCHEMBL206197

O=C(O)c1cccc(Cl)c1[N+](=O)[O-]

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.57
ALDH1A1 P00352 4/20 0.55
KMT2A Q03164 6/20 0.46
MEN1 O00255 5/20 0.46
CDK2 P24941 1/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP2D6 P10635 1/20 0.44
PBRM1 Q86U86 1/20 0.44
ALOX15 P16050 1/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
PLA2G1B P04054 2/20 0.43
MAPT P10636 2/20 0.43
ATG4B Q9Y4P1 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10824597 0.98 TSHR (0.55) TSHRALDH1A1KMT2AMEN1CDK2
SCHEMBL11002006 0.89 LMNA (0.47) TSHRALDH1A1KMT2AMEN1GRIN2D
SCHEMBL19213270 0.89 CES2 (0.52) TSHRALDH1A1KMT2AMEN1GRIN2D
SCHEMBL4833152 0.87 ALDH1A1 (0.45) TSHRALDH1A1KMT2AMEN1GRIN2D
SCHEMBL31441001 0.87 ALDH1A1 (0.45) TSHRALDH1A1KMT2AMEN1GRIN2D
SCHEMBL7115339 0.86 KMT2A (0.57) ALDH1A1KMT2AMEN1ALOX15PLA2G1B
SCHEMBL1497989 0.86 TSHR (0.60) TSHRALDH1A1KMT2AMEN1ALOX15
SCHEMBL8887009 0.85 KMT2A (0.44) TSHRALDH1A1KMT2AMEN1GRIN2D
SCHEMBL1625522 0.85 KMT2A (0.51) TSHRALDH1A1KMT2AMEN1GRIN2D
SCHEMBL27635677 0.85 TP53 (0.69) TSHRALDH1A1KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 524 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-114105800-B Preparation method of 2, 3-diaminomethyl benzoate 杭州国瑞生物科技有限公司 2023-09-01 CN claimed
CN-114105800-A Preparation method of 2, 3-diaminobenzoic acid methyl ester 杭州国瑞生物科技有限公司 2022-03-01 CN claimed
CN-107188841-B A kind of synthetic method of asymmetry diaryl list selenide compound 温州医科大学 2019-07-16 CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
CN-105621587-B A kind of method using potentiometric titrations degradating chloro nitro-aromatic 浙江大学 2018-01-23 CN claimed
CN-107188841-A A kind of synthetic method of asymmetric diaryl list selenide compound 温州医科大学 2017-09-22 CN claimed
CN-106707931-A Automatic building control system based on Agent and working method of automatic building control system 徐州工程学院 2017-05-24 CN claimed
WO-1994027584-A2 ARYLATING MEDICAMENTS RADOPATH LIMITED (GB) 1994-12-08 WO claimed
CN-1022333-C Method and composition for refinement of metal REM CHEMICALS INC (US) 1993-10-06 CN claimed
US-RE34272-E Oxalic acid, a thiocyanate salt, and a nitrobenzenesulfonate salt REM CHEMICALS, INC. (US) 1993-06-08 US claimed
EP-0395815-B1 METHOD AND COMPOSITION FOR REFINEMENT OF METAL SURFACES REM CHEMICALS, INC. (US) 1993-06-02 EP claimed
CN-1046946-A Be used for metallic surface method for finishing manufactured and composition REM CHEMICALS INC (US) 1990-11-14 CN claimed
EP-0395815-A1 Method and composition for refinement of metal surfaces REM CHEMICALS, INC. (US) 1990-11-07 EP claimed
US-4906327-A Method and composition for refinement of metal surfaces REM CHEMICALS, INC. (US) 1990-03-06 US claimed
US-4866204-A OXIDATION WITH METAL ACETYLACETONATES, PORPYRINS OR PHTHALOCYANINE CATALYSTS NOBEL CHEMICALS AB (SE) 1989-09-12 US claimed
US-4548791-A Thallium-containing composition for stripping palladium AMERICAN CHEMICAL & REFINING COMPANY, INC. (US) 1985-10-22 US claimed
US-3935005-A Composition and method for stripping gold and silver AMERICAN CHEMICAL & REFINING COMPANY, INCORPORATED (US) 1976-01-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS TSHR 1605/4885ALDH1A1 3087/4885KMT2A 2681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.