SCHEMBL711538

SCHEMBL711538

Nc1ccc(C(F)(F)F)c(N)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.60
GAA P10253 2/20 0.60
GLA P06280 1/20 0.60
POLB P06746 1/20 0.60
KIF11 P52732 5/20 0.50
KDM4E B2RXH2 4/20 0.43
ALDH1A1 P00352 4/20 0.43
CASP1 P29466 3/20 0.43
AR P10275 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
HSD17B10 Q99714 2/20 0.43
MAPK1 P28482 1/20 0.43
SRC P12931 1/20 0.43
HPGD P15428 1/20 0.43
CASP7 P55210 1/20 0.43
ATM Q13315 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TLR9 Q9NR96 1/20 0.43
NR1H2 P55055 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29460325 1.00 TSHR (0.60) TSHRGAAGLAPOLBKIF11
SCHEMBL3784954 0.82 KIF11 (0.69) TSHRGAAGLAPOLBKIF11
SCHEMBL29420085 0.82 TSHR (0.70) TSHRGAAGLAPOLBKIF11
SCHEMBL827884 0.82 TSHR (0.70) TSHRGAAGLAPOLBKIF11
SCHEMBL29140652 0.81 TSHR (0.45) TSHRGAAGLAPOLBKIF11
SCHEMBL2808894 0.80 TSHR (0.67) TSHRGAAGLAPOLBKIF11
SCHEMBL670777 0.80 GAA (0.67) TSHRGAAGLAPOLBKIF11
SCHEMBL29402330 0.80 GAA (0.67) TSHRGAAGLAPOLBKIF11
SCHEMBL8174858 0.80 KIF11 (0.61) TSHRGAAGLAPOLBKIF11
SCHEMBL330502 0.78 ALDH1A1 (0.52) TSHRGAAGLAPOLBKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11021606-B2 Multilayer film for electronic circuitry applications E I DU PONT DE NEMOURS AND COMPANY (US) 2021-06-01 US claimed
US-20150133628-A1 POLYAMINE AND METHOD FOR PRODUCING THEREOF RHODIA OPERATIONS (FR) 2015-05-14 US claimed
CN-102753604-B Polyamine and method for producing the same RHODIA OPERATIONS 2015-01-21 CN claimed
US-20130171459-A1 POLYAMIC ACID RESIN SOLUTION CONTAINING INTERPENETRATING POLYMER AND LAMINATE USING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-07-04 US claimed
US-20130123542-A1 POLYAMINE AND METHOD FOR PRODUCING THEREOF RHODIA OPERATIONS (FR) 2013-05-16 US claimed
EP-2522688-A1 POLYAMINE AND METHOD FOR PRODUCING THE SAME Rhodia Operations (FR) 2012-11-14 EP claimed
CN-102753604-A Polyamine and method for producing the same RHODIA OPERATIONS 2012-10-24 CN claimed
CN-102557965-A Preparation method for 2,4-diamido-benzotrifluoride SHANGHAI SINOFLUORO SCIENT CO 2012-07-11 CN claimed
EP-1431984-A1 Polymer resistor composition having a substantially neutral temperature coefficient of resistance and methods and compositions relating thereto E. I. du Pont de Nemours and Company (US) 2004-06-23 EP claimed
US-20040113127-A1 Resistor compositions having a substantially neutral temperature coefficient of resistance and methods and compositions relating thereto E.I. DU PONT DE NEMOURS AND COMPANY 2004-06-17 US claimed
US-20260102993-A1 ELECTRICALLY INSULATING LAMINATES FOR ELECTRIC MACHINE APPLICATIONS DUPONT ELECTRONICS INC (US) 2026-04-16 US disclosed
US-12564050-B2 Thermal substrates DUPONT ELECTRONICS, INC. 2026-02-24 US disclosed
US-20260022099-A1 ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF NEXYS THERAPEUTICS, INC. (US) 2026-01-22 US disclosed
US-20250382496-A1 PROCESSES FOR FORMING CROSSLINKED POLYMER FILMS DUPONT ELECTRONICS INC (US) 2025-12-18 US disclosed
US-12442084-B2 Metal-clad polymer films and electronic devices DUPONT ELECTRONICS, INC. (US) 2025-10-14 US disclosed
US-4853452-A Novel soluble polyimidesiloxanes and methods for their preparation using a flourine containing anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1989-08-01 US disclosed
US-4829131-A WIRE AND CABLE COATING, CURABLE OCCIDENTAL CHEMICAL CORPORATION (US) 1989-05-09 US disclosed
EP-0284803-A2 Novel soluble polymidesiloxanes and methods for their preparation and use Occidental Chemical Corporation (US) 1988-10-05 EP disclosed
US-4731450-A Process for perfluoroalkylation of aromatic derivatives RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-03-15 US disclosed
US-4107316-A Fluorurated amides of nicotinic acid and the process for the preparation thereof SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1978-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260102993-A1 ELECTRICALLY INSULATING LAMINATES FOR ELECTRIC MACHINE APPLICATIONS AS3MT, SMCHD1, ASH2L TSHR 2507/4885GAA 2334/4885GLA 3812/4885
US-20260022099-A1 ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF AHR, NR1H4, CNR1 TSHR 254/4885GAA 3845/4885GLA 3583/4885
US-12564050-B2 Thermal substrates TTN, AS3MT, SCO2 TSHR 2803/4885GAA 3208/4885GLA 1644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.