Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8172805 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL6671502 | 0.85 | ESR1 (0.40) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL8480050 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL24852666 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL185847 | 0.81 | CES2 (0.50) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL161784 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL29505675 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL16467229 | 0.79 | POLQ (0.48) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL3657472 | 0.79 | POLQ (0.48) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL24852672 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EPKMHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930593-A | Near infrared fluorescent probe for detecting cyclic hypoxia and preparation method and application thereof | 南通大学 | 2025-05-06 | — | — | CN | claimed |
| CN-119661626-A | Synthesis method of dutasteride impurity | 湖南科瑞生物制药股份有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-114113363-B | Method for detecting impurities in dutasteride soft capsules | 人福普克药业（武汉）有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-117466967-A | Preparation method of dutasteride | 湖南玉新药业有限公司 | 2024-01-30 | — | — | CN | claimed |
| CN-110950923-B | Method for recovering dutasteride from dutasteride mother liquor | 湖北葛店人福药业有限责任公司 | 2022-12-23 | — | — | CN | claimed |
| CN-114113363-A | Method for detecting impurities in dutasteride soft capsules | 人福普克药业（武汉）有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-109490444-B | Method for separating and measuring degradation impurities in dutasteride raw material medicine and preparation by HPLC (high performance liquid chromatography) method | 重庆华邦制药有限公司 | 2021-06-01 | — | — | CN | claimed |
| CN-110845310-A | Method for iodinating ortho-position of benzaldehyde compound | 平顶山学院 | 2020-02-28 | — | — | CN | claimed |
| EP-2238152-B1 | PROCESSES FOR PREPARATION OF DUTASTERIDE | GADOR SA (AR) | 2015-02-18 | — | — | EP | claimed |
| EP-2414378-B1 | SEPARATION OF 4-AZA-ANDROST-1-ENE-17-OIC ACID FROM 4-AZA-ANDROSTAN-17-OIC ACID | PHF SA (CH) | 2014-03-05 | — | — | EP | claimed |
| US-20090203724-A1 | SOLID AND CRYSTALLINE DUTASTERIDE AND PROCESSES FOR PREPARATION THEREOF | GADOR S.A. (AR) | 2009-08-13 | — | — | US | claimed |
| WO-2009083258-A2 | SOLID AND CRYSTALLINE DUTASTERIDE AND PROCESSES FOR PREPARATION THEREOF | GADOR S.A. (AR) | 2009-07-09 | — | — | WO | claimed |
| EP-1468983-B1 | PROCESS FOR PRODUCING 2,5-BIS(TRIFLUOROMETHYL)NITROBENZENE | ASAHI GLASS CO LTD (JP) | 2007-11-21 | — | — | EP | claimed |
| US-7038050-B2 | Method for the preparation of highly pure 1-androstene derivatives | HANMI PHARM. CO., LTD. (KR) | 2006-05-02 | — | — | US | claimed |
| EP-1646640-A1 | METHOD FOR THE PREPARATION OF HIGHLY PURE 1-ANDROSTENE DERIVATIVES | Hanmi Pharm. Co., Ltd. (KR) | 2006-04-19 | — | — | EP | claimed |
| US-20050245744-A1 | Method for the preparation of highly pure 1-androstene derivatives | HANMI PHARM. CO., LTLD. (KR) | 2005-11-03 | — | — | US | claimed |
| US-6930214-B2 | Process for producing 2,5-bis(trifluoromethyl)nitrobenzene | ASAHI GLASS COMPANY, LIMITED (JP) | 2005-08-16 | — | — | US | claimed |
| WO-2005007670-A1 | METHOD FOR THE PREPARATION OF HIGHLY PURE 1-ANDROSTENE DERIVATIVES | HANMI PHARM. CO., LTD. (KR) | 2005-01-27 | — | — | WO | claimed |
| US-20040242942-A1 | Process for producing 2,5-bis(trifluoromethyl)nitrobenzene | ASAHI GLASS COMPANY LIMITED (JP) | 2004-12-02 | — | — | US | claimed |
| EP-1468983-A1 | PROCESS FOR PRODUCING 2,5-BIS(TRIFLUOROMETHYL)NITROBENZENE | ASAHI GLASS COMPANY LTD. (JP) | 2004-10-20 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245744-A1 | Method for the preparation of highly pure 1-androstene derivatives | CYP19A1, HSD17B11, CYP17A1 | ALDH1A1 252/4885KDM4E 4514/4885PKM 3627/4885 |
| US-20090203724-A1 | SOLID AND CRYSTALLINE DUTASTERIDE AND PROCESSES FOR PREPARATION THEREOF | AR, CYP21A2, CYP4A22 | ALDH1A1 1010/4885KDM4E 286/4885PKM 4184/4885 |
| US-20040242942-A1 | Process for producing 2,5-bis(trifluoromethyl)nitrobenzene | NOS2, NOS1, NOX5 | ALDH1A1 1871/4885KDM4E 2896/4885PKM 2230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.