Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.49 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13907302 | 0.80 | CYP19A1 (0.56) | TBXAS1CYP19A1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL15556913 | 0.77 | CYP19A1 (0.59) | TBXAS1CYP19A1HMOX1KMT2AMEN1 | |
| SCHEMBL20701924 | 0.76 | PRKCI (0.53) | TBXAS1CYP19A1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL15179017 | 0.76 | CYP19A1 (0.64) | TBXAS1CYP19A1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL27460992 | 0.75 | TBXAS1 (0.60) | TBXAS1CYP19A1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL4316370 | 0.75 | CYP11B1 (0.69) | TBXAS1CYP19A1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL409741 | 0.74 | HMOX1 (0.72) | TBXAS1CYP19A1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL18940356 | 0.73 | CYP11B1 (0.49) | TBXAS1CYP19A1CYP11B1CYP11B2KMT2A | |
| SCHEMBL27508985 | 0.73 | CYP11B1 (0.51) | TBXAS1CYP19A1CYP11B1CYP11B2HMOX1 | |
| Bromide SCHEMBL29223796 | 0.73 | HMOX1 (0.70) | TBXAS1CYP19A1CYP11B1CYP11B2HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003026664-A1 | 2-PHENYLAMINO-4- (5-PYRAZOLYLAMINO) -PYRAMIDINE DERIVATIVES AS KINASE INHIBITORS, IN PARTICULAR, SRC KINASE INHIBITORS | BAYER CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |