Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HMOX1 | P09601 | 3/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27508985 | 0.87 | CYP11B1 (0.51) | TBXAS1CYP19A1KMT2AHMOX1CYP11B1 | |
| SCHEMBL4316370 | 0.86 | CYP11B1 (0.69) | TBXAS1CYP19A1KMT2AHMOX1CYP11B1 | |
| SCHEMBL570591 | 0.83 | CYP11B1 (0.66) | TBXAS1CYP19A1KMT2AHMOX1CYP11B1 | |
| SCHEMBL10788342 | 0.82 | TBXAS1 (0.65) | TBXAS1CYP19A1KMT2AHMOX1 | |
| SCHEMBL6986190 | 0.82 | HMOX1 (0.79) | TBXAS1CYP19A1KMT2AHMOX1CYP11B1 | |
| SCHEMBL16719036 | 0.82 | CYP19A1 (0.81) | TBXAS1CYP19A1KMT2AHMOX1CYP11B1 | |
| SCHEMBL6987156 | 0.82 | CYP19A1 (0.69) | TBXAS1CYP19A1KMT2AHMOX1CYP11B1 | |
| SCHEMBL7284368 | 0.81 | CYP11B1 (0.73) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL409741 | 0.81 | HMOX1 (0.72) | TBXAS1CYP19A1KMT2AHMOX1CYP11B1 | |
| Hydrochloric Acid SCHEMBL7527357 | 0.80 | HMOX1 (0.70) | TBXAS1CYP19A1KMT2AHMOX1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1068118-A | Imidazo [2, 1-b ] [3] benzazepine derivatives, compositions and methods of use | JANSSEN PHARMACEUTICA NV (BE) | 1993-01-20 | — | — | CN | disclosed |