Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | MMP7 | P09237 | 3/20 | 0.34 |
| ▸ | MMP12 | P39900 | 3/20 | 0.34 |
| ▸ | MMP13 | P45452 | 3/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5189237 | 0.85 | CA2 (0.46) | KDM4EMEN1RECQLKMT2ATSHR | |
| SCHEMBL10633182 | 0.81 | PRSS1 (0.40) | KDM4EMEN1RECQLKMT2ATSHR | |
| SCHEMBL10636059 | 0.81 | PRSS1 (0.40) | KDM4EMEN1RECQLKMT2ATSHR | |
| SCHEMBL10636373 | 0.80 | PRSS1 (0.40) | KDM4EMEN1RECQLKMT2ATSHR | |
| SCHEMBL10636634 | 0.80 | PRSS1 (0.40) | KDM4EMEN1RECQLKMT2ATSHR | |
| SCHEMBL10633340 | 0.80 | PRSS1 (0.40) | KDM4EMEN1RECQLKMT2ATSHR | |
| SCHEMBL9566688 | 0.80 | PRSS1 (0.40) | KDM4EMEN1RECQLKMT2ATSHR | |
| SCHEMBL6152590 | 0.79 | KDM4E (0.60) | KDM4EMEN1RECQLKMT2ACA12 | |
| SCHEMBL7030621 | 0.78 | KDM4E (0.55) | KDM4EMEN1RECQLKMT2ACA12 | |
| SCHEMBL9351922 | 0.78 | ALDH1A1 (0.54) | KDM4EMEN1RECQLKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292566-A2 | PROCESS FOR HYDROLYZING AMIDO-CARBOXYLIC ACID ESTERS INTO AMIDO-CARBOXYLIC ACIDS | EASTMAN CHEMICAL COMPANY (US) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001092209-A2 | PROCESS FOR HYDROLYZING AMIDO-CARBOXYLIC ACID ESTERS INTO AMIDO-CARBOXYLIC ACIDS | EASTMAN CHEMICAL COMPANY (US) | 2001-12-06 | — | — | WO | disclosed |