Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 4/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110509 | 0.89 | TTR (0.45) | TTRPIK3CAMTORPIK3CGMEN1 | |
| SCHEMBL14098146 | 0.86 | ALOX5 (0.40) | TTRPIK3CAMTORPIK3CGMEN1 | |
| SCHEMBL5112851 | 0.83 | PIK3CA (0.41) | TTRPIK3CAMTORPIK3CGMEN1 | |
| SCHEMBL7112820 | 0.83 | ALDH1A1 (0.40) | TTRPIK3CAMTORMEN1KMT2A | |
| SCHEMBL7110722 | 0.81 | CYP19A1 (0.48) | TTRPIK3CAMTORPIK3CGMEN1 | |
| SCHEMBL14098187 | 0.81 | CYP19A1 (0.45) | TTRMEN1KMT2AALDH1A1CYP19A1 | |
| SCHEMBL7116053 | 0.81 | ALDH1A1 (0.45) | TTRMEN1KMT2AALDH1A1CYP19A1 | |
| SCHEMBL14098123 | 0.80 | ALDH1A1 (0.41) | TTRMEN1KMT2AALDH1A1CYP19A1 | |
| SCHEMBL5112986 | 0.80 | CYP19A1 (0.45) | TTRPIK3CAMTORPIK3CGMEN1 | |
| SCHEMBL14098190 | 0.80 | CYP19A1 (0.42) | TTRMEN1KMT2AALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065021-A1 | Tracheal smooth muscle relaxants | YAMASHITA SHINYA (JP) | 2003-04-03 | — | — | US | disclosed |
| US-6495592-B1 | DIBENZ(B,F)OXEPIN DERIVATIVES; ANTIASTHMATICS | NIPPON SUISAN KAISHA, LTD. (JP) | 2002-12-17 | — | — | US | disclosed |
| EP-0805155-B1 | NOVEL ANTIOXIDANT TRICYCLIC FUSED HETEROCYCLIC COMPOUND | NIPPON SUISAN KAISHA LTD (JP) | 2002-03-13 | — | — | EP | disclosed |
| US-6180659-B1 | USING A DIBENZO(B,F)-(OXEPIN OR THIEPIN) COMPOUND | NIPPON SUISAN KAISHA, LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0885610-A1 | TRACHEAL SMOOTH MUSCLE RELAXANT | NIPPON SUISAN KAISHA, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0805155-A1 | NOVEL ANTIOXIDANT TRICYCLIC FUSED HETEROCYCLIC COMPOUND | NIPPON SUISAN KAISHA, LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065021-A1 | Tracheal smooth muscle relaxants | MYLK, MUSK, CPT1B | TTR 3878/4885PIK3CA 3899/4885MTOR 2901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.