Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL1331252 | 0.95 | — | — | |
| Succinic Acid SCHEMBL4269130 | 0.95 | LMNA (1.00) | — | |
| Succinic Acid SCHEMBL1331200 | 0.95 | — | — | |
| Succinic Acid SCHEMBL4269135 | 0.95 | LMNA (1.00) | — | |
| Succinic Acid SCHEMBL3799615 | 0.95 | — | — | |
| Succinic Acid SCHEMBL29808469 | 0.95 | — | — | |
| Succinic Acid SCHEMBL24696 | 0.95 | LMNA (1.00) | — | |
| Succinic Acid SCHEMBL829 | 0.95 | — | — | |
| Succinic Acid SCHEMBL21867134 | 0.95 | LMNA (1.00) | — | |
| Succinic Acid SCHEMBL8992010 | 0.95 | LMNA (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946584-B1 | Meiosis regulating compounds | NOVO NORDISK AS (DK) | 2003-04-23 | — | — | EP | claimed |