SCHEMBL7117337

SCHEMBL7117337

CCO[Si](OCC)(OCC)OC(C)Oc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
MAOA P21397 2/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
MAOB P27338 1/20 0.38
NISCH Q9Y2I1 1/20 0.38
LTA4H P09960 1/20 0.36
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
LMNA P02545 2/20 0.35
POLB P06746 2/20 0.34
ALDH1A1 P00352 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
SLC6A4 P31645 1/20 0.33
ALPL P05186 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7116665 0.96 KDM4E (0.40) KDM4EMAOAADRA2AADRA2BADRA2C
SCHEMBL7111568 0.79 KDM4E (0.43) KDM4EMAOAADRA2AADRA2BADRA2C
SCHEMBL7114275 0.79 KDM4E (0.43) KDM4EMAOAADRA2AADRA2BADRA2C
SCHEMBL28840541 0.76 LTB4R (0.33) ADRA2AADRA2BADRA2CLMNAPOLB
SCHEMBL997422 0.75 LMNA (0.46) KDM4EMAOAADRA2AADRA2BADRA2C
SCHEMBL10627325 0.74 ADRA2A (0.37) ADRA2AADRA2BADRA2CLMNAPOLB
SCHEMBL28257779 0.74 MAOA (0.40) KDM4EMAOAADRA2AADRA2BADRA2C
SCHEMBL28840924 0.73 LTB4R (0.32) ADRA2AADRA2BADRA2CLMNAPOLB
SCHEMBL28840488 0.73 LTB4R (0.32) ADRA2AADRA2BADRA2CLMNAPOLB
SCHEMBL28840540 0.73 SMN1; SMN2 (0.35) TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0754739-B1 Curable coating composition KANSAI PAINT CO LTD (JP) 2003-10-29 EP disclosed
US-5684095-A POLYESTER, POLYEPOXIDE, SILICON COMPOUND AND CHELATE CMPOUND IN SOLVENT KANSAI PAINT COMPANY, LIMITED (JP) 1997-11-04 US disclosed
EP-0754739-A2 Curable coating composition KANSAI PAINT CO., LTD. (JP) 1997-01-22 EP disclosed