Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111186 | 0.66 | CRHBP (0.62) | MPOCYP2C19HIF1AKDM4EALDH1A1 | |
| SCHEMBL7673716 | 0.63 | GAA (0.43) | MPOHIF1AKDM4EALDH1A1GAA | |
| SCHEMBL7114819 | 0.63 | KDM4E (0.64) | CYP2C19KDM4EALDH1A1GAAMAPT | |
| SCHEMBL3278648 | 0.62 | HTR7 (0.43) | — | |
| SCHEMBL7118356 | 0.61 | SIGMAR1 (0.42) | MPOKDM4EALDH1A1GAAMAPT | |
| SCHEMBL906627 | 0.61 | — | — | |
| SCHEMBL1626873 | 0.61 | — | — | |
| SCHEMBL11846421 | 0.59 | HSD17B10 (0.50) | CYP2C19HIF1AKDM4EALDH1A1MAPT | |
| SCHEMBL10782682 | 0.59 | HSD17B10 (0.50) | CYP2C19HIF1AKDM4EALDH1A1MAPT | |
| SCHEMBL28176204 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353636-A1 | NOVEL COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | P & G-Clairol, Inc. (US) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002094208-A1 | NOVEL COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | P & G - CLAIROL, INC. (US) | 2002-11-28 | — | — | WO | disclosed |
| US-20020147193-A1 | Novel couplers for use in oxidative hair dyeing | CLAIROL INCORPORATED | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147193-A1 | Novel couplers for use in oxidative hair dyeing | CBR1, CBR3, MT-CO1 | MPO 112/4885CYP2C19 673/4885HIF1A 1318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.