Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124462 | 0.89 | GAA (0.45) | ALDH1A1GAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7127820 | 0.86 | GHSR (0.43) | ALDH1A1L3MBTL1GAACA2CA12 | |
| SCHEMBL7127023 | 0.85 | GHSR (0.42) | ALDH1A1L3MBTL1GAACA2CA12 | |
| SCHEMBL7126170 | 0.85 | F2 (0.46) | ALDH1A1L3MBTL1SMN1; SMN2CA2MEN1 | |
| SCHEMBL7121674 | 0.83 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2PPARAMAPT | |
| SCHEMBL7125294 | 0.83 | KMT2A (0.58) | ALDH1A1L3MBTL1GAACA2MEN1 | |
| SCHEMBL6925851 | 0.76 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1GAASMN1; SMN2PPARA | |
| SCHEMBL7116832 | 0.75 | CA9 (0.39) | NPC1RAB9ACA2CA12CA9 | |
| SCHEMBL18221866 | 0.75 | CYP19A1 (0.53) | ALDH1A1L3MBTL1GAAPPARACA2 | |
| SCHEMBL14676346 | 0.70 | CA2 (0.56) | ALDH1A1L3MBTL1GAASMN1; SMN2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583318-B2 | Carrying out a four component condensation reaction between components consisting of a sulfonamide, an aldehyde or ketone, an isocyanide and a carboxylic acid, and one of such components being attached to a solid support | ADVANCED SYNTECH, LLC | 2003-06-24 | — | — | US | disclosed |
| US-20030013910-A1 | Method for synthesis of alpha-sulfonamido amide, carboxylic acid and hydroxamic acid derivatives | ADVANCED SYNTECH LLC | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013910-A1 | Method for synthesis of alpha-sulfonamido amide, carboxylic acid and hydroxamic acid derivatives | ASPH, COASY, HAAO | ALDH1A1 391/4885L3MBTL1 4407/4885GAA 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.