Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.32 |
| ▸ | PARG | Q86W56 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122557 | 0.90 | F10 (0.55) | F10F2PRSS1 | |
| SCHEMBL7119405 | 0.89 | F10 (0.48) | F10F2PRSS1PARGBRD4 | |
| SCHEMBL7121927 | 0.82 | F10 (0.46) | F10F2PRSS1PARGBRD4 | |
| SCHEMBL7128478 | 0.78 | F10 (0.54) | F10F2 | |
| SCHEMBL7119002 | 0.74 | F10 (0.82) | F10 | |
| SCHEMBL7126894 | 0.70 | F10 (0.51) | F10F2 | |
| SCHEMBL7126472 | 0.69 | PARG (0.43) | PARG | |
| SCHEMBL7121882 | 0.69 | RAB9A (0.38) | PARGBRD4JAK2 | |
| SCHEMBL7125714 | 0.68 | MDM2 (0.42) | PARG | |
| SCHEMBL7122554 | 0.66 | F10 (1.00) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114448-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114448-A1 | Inhibitors of factor Xa | SERPINC1, F11, TFPI | F10 7/4885F2 5/4885PRSS1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.