SCHEMBL7121882

SCHEMBL7121882

CC(C)(C)NS(=O)(=O)c1cccc(C2c3ccccc3C(=O)N2CCOc2ccc3cc(Br)ccc3c2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.38
HTR1A P08908 8/20 0.37
HTR7 P34969 8/20 0.37
BRD4 O60885 2/20 0.36
JAK2 O60674 2/20 0.36
BMPR1B O00238 1/20 0.36
PLK4 O00444 1/20 0.36
STK25 O00506 1/20 0.36
CIT O14578 1/20 0.36
RIOK3 O14730 1/20 0.36
CHEK1 O14757 1/20 0.36
IKBKB O14920 1/20 0.36
CASK O14936 1/20 0.36
AURKA O14965 1/20 0.36
GAK O14976 1/20 0.36
DCLK1 O15075 1/20 0.36
CHUK O15111 1/20 0.36
MUSK O15146 1/20 0.36
EPHB6 O15197 1/20 0.36
MLNR O43193 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7119306 0.86 RAB9A (0.41) RAB9AHTR1AHTR7NPC1MAPT
SCHEMBL7121927 0.86 F10 (0.46) RAB9ABRD4JAK2BMPR1BPLK4
SCHEMBL7129114 0.85 MGLL (0.37) RAB9AHTR1AHTR7BRD4JAK2
SCHEMBL7117838 0.76 KDM4E (0.43) RAB9AKCNH2KDM4EMEN1NPC1
SCHEMBL7128790 0.74 CYP1A2 (0.42) RAB9AKDM4EMEN1NPC1LMNA
SCHEMBL7121877 0.69 F10 (0.57) ALDH1A1
SCHEMBL7119405 0.69 F10 (0.48) BRD4JAK2PARG
SCHEMBL7119005 0.69 F10 (0.49) BRD4JAK2PARG
SCHEMBL7126472 0.67 PARG (0.43) RAB9AKDM4EMEN1NPC1LMNA
SCHEMBL7125714 0.67 MDM2 (0.42) RAB9AKDM4EMEN1NPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030114448-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2003-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030114448-A1 Inhibitors of factor Xa SERPINC1, F11, TFPI RAB9A 1523/4885HTR1A 3792/4885HTR7 3396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.