Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103904 | 0.89 | MAOB (0.61) | MAOAMAOBGSK3BALDH1A1CA12 | |
| SCHEMBL30757515 | 0.89 | MAOB (0.61) | MAOAMAOBGSK3BALDH1A1CA12 | |
| 1,4-Dimethoxybenzene SCHEMBL28617696 | 0.89 | MAOB (0.61) | MAOAMAOBGSK3BALDH1A1CA12 | |
| SCHEMBL30250275 | 0.87 | MAOA (0.59) | MAOAMAOBGSK3BALDH1A1CA12 | |
| SCHEMBL91929 | 0.83 | MAOA (0.56) | MAOAMAOBGSK3BALDH1A1CA12 | |
| SCHEMBL921496 | 0.83 | MAOA (0.56) | MAOAMAOBGSK3BALDH1A1CA12 | |
| SCHEMBL3419967 | 0.83 | MAOA (0.56) | MAOAMAOBGSK3BALDH1A1CA12 | |
| SCHEMBL13863705 | 0.83 | APP (0.63) | MAOAMAOBGSK3BALDH1A1CA12 | |
| SCHEMBL7828090 | 0.81 | MAOA (0.54) | MAOAMAOBGSK3BALDH1A1CA12 | |
| SCHEMBL13241213 | 0.80 | MAOA (0.50) | MAOAMAOBGSK3BALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566360-B1 | Administering 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position for therapy of hypertrophy of the prostate, incontinence or female sexual dysfunction in mammals | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-20 | — | — | US | disclosed |