Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763484 | 0.92 | MAPT (0.55) | TP53GAATRPV1POLBKDM4E | |
| SCHEMBL7120573 | 0.85 | TP53 (0.55) | TP53GAATRPV1POLBKDM4E | |
| SCHEMBL7762753 | 0.81 | TRPV1 (0.62) | TP53GAATRPV1POLBKDM4E | |
| SCHEMBL2915657 | 0.79 | TRPV1 (0.72) | TP53GAATRPV1POLBKDM4E | |
| SCHEMBL2019464 | 0.78 | POLB (0.70) | TP53GAATRPV1POLBNPC1 | |
| SCHEMBL7190666 | 0.77 | TRPV1 (0.61) | TP53GAATRPV1POLBKDM4E | |
| SCHEMBL27824665 | 0.77 | TP53 (0.56) | TP53GAATRPV1POLBKDM4E | |
| SCHEMBL16088671 | 0.76 | TRPV1 (0.56) | TP53GAATRPV1POLBKDM4E | |
| SCHEMBL7113169 | 0.76 | SNCA (0.54) | GAAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2119500 | 0.76 | FFAR1 (0.66) | TP53GAATRPV1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212074-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212074-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A3, SLC34A1 | TP53 4292/4885GAA 420/4885TRPV1 1422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.