Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119449 | 0.92 | TP53 (0.60) | MAPTGAAALDH1A1HPGDMEN1 | |
| SCHEMBL7114663 | 0.86 | NPC1 (0.58) | MAPTGAAALDH1A1HPGDMEN1 | |
| SCHEMBL2119008 | 0.81 | TRPV1 (0.70) | MAPTGAAALDH1A1HPGDMEN1 | |
| SCHEMBL12338996 | 0.81 | TRPV1 (0.70) | MAPTGAAALDH1A1HPGDMEN1 | |
| SCHEMBL19234762 | 0.80 | SAE1 (0.69) | MAPTGAAALDH1A1HPGDMEN1 | |
| SCHEMBL7120573 | 0.78 | TP53 (0.55) | MAPTGAAALDH1A1HPGDLMNA | |
| SCHEMBL7762753 | 0.74 | TRPV1 (0.62) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27803870 | 0.73 | TP53 (0.50) | MAPTGAAALDH1A1HPGDMEN1 | |
| SCHEMBL2915657 | 0.72 | TRPV1 (0.72) | MAPTGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2019464 | 0.72 | POLB (0.70) | MAPTGAAALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001082924-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |