Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120573 | 0.95 | TP53 (0.55) | TRPV1TP53GAAAKR1C2AKR1C1 | |
| SCHEMBL7114764 | 0.83 | GAA (0.53) | TP53GAANPC1RAB9AALDH1A1 | |
| SCHEMBL7119485 | 0.82 | LMNA (0.54) | TP53GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7119449 | 0.81 | TP53 (0.60) | TRPV1TP53GAANPC1RAB9A | |
| SCHEMBL16088642 | 0.78 | PLK1 (0.56) | TRPV1TP53GAANPC1RAB9A | |
| SCHEMBL13181111 | 0.77 | TRPV1 (0.88) | TRPV1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL4107205 | 0.77 | TRPV1 (0.72) | TRPV1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7763476 | 0.76 | SMN1; SMN2 (0.64) | TP53GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16088657 | 0.76 | PLK1 (0.58) | TRPV1TP53GAANPC1RAB9A | |
| SCHEMBL24539597 | 0.76 | TRPV1 (0.58) | TRPV1GAANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001082924-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |