Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762753 | 0.95 | TRPV1 (0.62) | TP53GAATRPV1NPC1RAB9A | |
| SCHEMBL7119485 | 0.86 | LMNA (0.54) | TP53GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7119449 | 0.85 | TP53 (0.60) | TP53GAATRPV1NPC1RAB9A | |
| SCHEMBL7763476 | 0.80 | SMN1; SMN2 (0.64) | TP53GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9827917 | 0.79 | ACLY (0.60) | AKR1C2AKR1C1ACLYMAPK1ALOX15 | |
| SCHEMBL7114636 | 0.79 | SMN1; SMN2 (0.69) | TP53GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2915657 | 0.78 | TRPV1 (0.72) | TP53GAATRPV1NPC1RAB9A | |
| SCHEMBL7113343 | 0.78 | KMT2A (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL7763484 | 0.78 | MAPT (0.55) | TP53GAATRPV1NPC1RAB9A | |
| SCHEMBL7116292 | 0.78 | P2RX1 (0.56) | NPC1SMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212074-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-13 | — | — | US | claimed |
| US-20030212074-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-13 | — | — | US | disclosed |
| WO-2001082924-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212074-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A3, SLC34A1 | TP53 4292/4885GAA 420/4885TRPV1 1422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.