Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609664 | 0.79 | ADRA2C (0.51) | MLYCDTSHRALDH1A1GLAPOLB | |
| SCHEMBL5353769 | 0.76 | ALDH1A1 (0.51) | MLYCDTSHRALDH1A1GLAPOLB | |
| SCHEMBL8439016 | 0.76 | ALDH1A1 (0.47) | MLYCDTSHRALDH1A1GLAHSD17B10 | |
| SCHEMBL29873818 | 0.74 | ALDH1A1 (0.46) | MLYCDTSHRALDH1A1GLAPOLB | |
| SCHEMBL28294373 | 0.74 | ALDH1A1 (0.46) | MLYCDTSHRALDH1A1GLAPOLB | |
| SCHEMBL6901524 | 0.73 | MLYCD (0.50) | MLYCDTSHRALDH1A1GLASMN1; SMN2 | |
| SCHEMBL8858955 | 0.72 | ALDH1A1 (0.57) | MLYCDTSHRALDH1A1GLAPOLB | |
| SCHEMBL10541028 | 0.72 | MLYCD (0.49) | MLYCDTSHRALDH1A1GLASMN1; SMN2 | |
| SCHEMBL20314798 | 0.71 | GSTO1 (0.58) | MLYCDTSHRALDH1A1GLASMN1; SMN2 | |
| SCHEMBL6295798 | 0.71 | MLYCD (0.48) | MLYCDTSHRALDH1A1GLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | CAO JINGRONG (US) | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | GSK3B, GSK3A, GSKIP | MLYCD 2993/4885TSHR 3679/4885ALDH1A1 3164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.