Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EBP | Q15125 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128706 | 0.84 | L3MBTL1 (0.43) | L3MBTL1EBPSIGMAR1FFAR1ALDH1A1 | |
| SCHEMBL7131088 | 0.84 | L3MBTL1 (0.43) | L3MBTL1EBPSIGMAR1TSHRFFAR1 | |
| SCHEMBL7123235 | 0.84 | L3MBTL1 (0.43) | L3MBTL1EBPSIGMAR1FFAR1ALDH1A1 | |
| SCHEMBL7129611 | 0.84 | L3MBTL1 (0.43) | L3MBTL1EBPSIGMAR1HIF1ACTSS | |
| SCHEMBL5751980 | 0.81 | EBP (0.51) | L3MBTL1EBPSIGMAR1TSHRHIF1A | |
| SCHEMBL10634290 | 0.80 | L3MBTL1 (0.44) | L3MBTL1EBPSIGMAR1 | |
| SCHEMBL7120088 | 0.78 | EBP (0.40) | EBPSIGMAR1TSHRHIF1ACYP2C9 | |
| SCHEMBL11823339 | 0.78 | CTSS (0.33) | TSHRHIF1ACYP2C9HSD17B10CTSS | |
| SCHEMBL7969206 | 0.77 | L3MBTL1 (0.40) | L3MBTL1EBPSIGMAR1CYP2D6CYP3A4 | |
| SCHEMBL10631481 | 0.76 | L3MBTL1 (0.41) | L3MBTL1EBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6667412-B1 | Carboxylic acid, ester or alcohol derivatives; n,n-substi-tuted cyclic amine or phenylacetonitrile intermediates; low cost; stability, workability, final product purity | EISAI CO., LTD. (JP) | 2003-12-23 | — | — | US | claimed |
| EP-1167348-A1 | NITRILE DERIVATIVES | Eisai Co., Ltd. (JP) | 2002-01-02 | — | — | EP | claimed |
| US-6667412-B1 | Carboxylic acid, ester or alcohol derivatives; n,n-substi-tuted cyclic amine or phenylacetonitrile intermediates; low cost; stability, workability, final product purity | EISAI CO., LTD. (JP) | 2003-12-23 | — | — | US | disclosed |
| EP-1167348-A1 | NITRILE DERIVATIVES | Eisai Co., Ltd. (JP) | 2002-01-02 | — | — | EP | disclosed |