Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 13/20 | 0.57 |
| ▸ | F2 | P00734 | 6/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | C1S | P09871 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10515327 | 0.83 | PPARG (0.56) | — | |
| SCHEMBL14408276 | 0.79 | PPARA (0.64) | — | |
| SCHEMBL6807930 | 0.79 | F10 (0.60) | F10PRSS1F2PLG | |
| SCHEMBL7117710 | 0.79 | PRSS1 (0.58) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL21881586 | 0.79 | KDM4E (0.55) | — | |
| SCHEMBL13324879 | 0.79 | KDM4E (0.55) | — | |
| SCHEMBL660871 | 0.79 | KDM4E (0.55) | — | |
| SCHEMBL6807765 | 0.79 | F10 (0.62) | F10PRSS1F2PLG | |
| SCHEMBL5166349 | 0.78 | F10 (0.66) | F10PRSS1F2 | |
| Hydrogen Sulfide SCHEMBL28780976 | 0.77 | KDM4E (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | claimed |
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | APOB, F12, SERPINB1 | F10 60/4885PRSS1 34/4885F2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.