Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.44 |
| ▸ | F13A1 | P00488 | 2/20 | 0.41 |
| ▸ | TGM2 | P21980 | 2/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | TGM1 | P22735 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.39 |
| ▸ | DTYMK | P23919 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9934456 | 0.79 | POLB (0.46) | GPR119ACKR3KDM1ACHRM2CHRM4 | |
| SCHEMBL9933703 | 0.77 | GPR119 (0.42) | GPR119F13A1TGM2ACKR3TGM1 | |
| SCHEMBL9963093 | 0.74 | GPR119 (0.44) | GPR119KDM1ACHRM2CHRM4CHRM1 | |
| SCHEMBL7120430 | 0.72 | MC4R (0.53) | STSGPR119 | |
| SCHEMBL1180627 | 0.71 | TGM2 (0.60) | F13A1TGM2TGM1PKMSMN1; SMN2 | |
| SCHEMBL16111449 | 0.70 | TP53 (0.61) | GPR119KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5336031 | 0.70 | STS (0.48) | STSGPR119CHRM2CHRM4CHRM1 | |
| SCHEMBL9285413 | 0.70 | GPR119 (0.50) | STSGPR119F13A1TGM2TGM1 | |
| SCHEMBL4473489 | 0.69 | POLB (0.61) | KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9933216 | 0.69 | ALDH1A1 (0.72) | GPR119KDM1ACHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358163-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059095-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |