Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.30 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285798 | 0.98 | ATAD2 (0.34) | ATAD2NOTUMNR1H2 | |
| SCHEMBL6290427 | 0.90 | ATAD2 (0.38) | ATAD2NOTUMNR1H2SLC6A2SLC6A4 | |
| SCHEMBL6287357 | 0.80 | — | — | |
| SCHEMBL24077067 | 0.73 | NOTUM (0.47) | ATAD2NOTUMNR1H2PDK1PDK2 | |
| SCHEMBL30727816 | 0.71 | ATAD2 (0.47) | ATAD2NOTUMNR1H2SLC6A2SLC6A4 | |
| SCHEMBL7120839 | 0.71 | ATAD2 (0.37) | ATAD2NR1H2PDK1PDK2PDK3 | |
| SCHEMBL28765957 | 0.70 | ATAD2 (0.42) | ATAD2NOTUMNR1H2PDK1PDK2 | |
| SCHEMBL7460173 | 0.70 | ATAD2 (0.32) | ATAD2 | |
| SCHEMBL28765958 | 0.67 | ATAD2 (0.42) | ATAD2NOTUMNR1H2PDK1PDK2 | |
| SCHEMBL6290425 | 0.67 | KDM4E (0.39) | ATAD2PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | claimed |
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, NDUFB5, NDUFB4 | ATAD2 3497/4885NOTUM 462/4885NR1H2 2261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.