Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 7/20 | 0.36 |
| ▸ | HTR2C | P28335 | 7/20 | 0.36 |
| ▸ | HTR2B | P41595 | 7/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462241 | 0.75 | HDAC6 (0.37) | — | |
| SCHEMBL6285793 | 0.74 | S1PR1 (0.41) | ATAD2S1PR1NR1H2 | |
| SCHEMBL6290427 | 0.74 | ATAD2 (0.38) | ATAD2ALDH1A1MAPTS1PR1NR1H2 | |
| SCHEMBL24077203 | 0.74 | HTR2A (0.46) | ATAD2ALDH1A1MAPTHTR2AHTR2C | |
| SCHEMBL6290425 | 0.74 | KDM4E (0.39) | ATAD2ALDH1A1MAPK1MAPTL3MBTL1 | |
| SCHEMBL6285804 | 0.73 | KDM4E (0.38) | ATAD2ALDH1A1MAPTL3MBTL1TDP1 | |
| SCHEMBL7120843 | 0.73 | KDM4E (0.38) | ATAD2ALDH1A1MAPTL3MBTL1TDP1 | |
| SCHEMBL18426670 | 0.72 | ATAD2 (0.43) | ATAD2ALDH1A1MAPK1MAPTL3MBTL1 | |
| SCHEMBL30168583 | 0.72 | ATAD2 (0.55) | ATAD2ALDH1A1MAPTL3MBTL1HTR2A | |
| SCHEMBL618018 | 0.72 | ATAD2 (0.55) | ATAD2ALDH1A1MAPTL3MBTL1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | claimed |
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, NDUFB5, NDUFB4 | ATAD2 3497/4885ALDH1A1 139/4885MAPK1 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.