Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | CASP1 | P29466 | 2/20 | 0.64 |
| ▸ | CASP7 | P55210 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.48 |
| ▸ | AGER | Q15109 | 2/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 5/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120862 | 0.84 | ALDH1A1 (0.61) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL144309 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL29356441 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1GAAHPGDCASP1 | |
| Glycine SCHEMBL9259892 | 0.78 | KDM4E (0.79) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL9297256 | 0.78 | KMT2A (0.62) | KDM4EALDH1A1GAAHPGDCASP1 | |
| Alanine SCHEMBL15556780 | 0.76 | KDM4E (0.75) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL7116354 | 0.71 | PARP1 (0.37) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL7973305 | 0.69 | KDM4E (0.77) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL1771156 | 0.69 | KDM4E (0.77) | KDM4EALDH1A1GAAHPGDCASP1 | |
| Proline SCHEMBL28395374 | 0.68 | TLR9 (0.57) | KDM4EALDH1A1GAAHPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6632629-B2 | Microfluidic in-line labeling method of continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES CORP. | 2003-10-14 | — | — | US | claimed |
| US-20030064425-A1 | Microfluidic in-line labeling method for continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES CORP. | 2003-04-03 | — | — | US | claimed |
| US-6468761-B2 | Microfluidic in-line labeling method for continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES, CORP. | 2002-10-22 | — | — | US | claimed |
| US-20010026929-A1 | Microfluidic in-line labeling method for continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES CORP. | 2001-10-04 | — | — | US | claimed |
| EP-0533200-A1 | Preparation and use of novel activated carbamates | WATERS INVESTMENTS LIMITED (US) | 1993-03-24 | — | — | EP | claimed |
| US-6632629-B2 | Microfluidic in-line labeling method of continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES CORP. | 2003-10-14 | — | — | US | disclosed |
| US-20030064425-A1 | Microfluidic in-line labeling method for continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES CORP. | 2003-04-03 | — | — | US | disclosed |
| US-6468761-B2 | Microfluidic in-line labeling method for continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES, CORP. | 2002-10-22 | — | — | US | disclosed |
| US-20010026929-A1 | Microfluidic in-line labeling method for continuous-flow protease inhibition analysis | CALIPER TECHNOLOGIES CORP. | 2001-10-04 | — | — | US | disclosed |