Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.45 |
| ▸ | FCER2 | P06734 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP7 | P09237 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20393464 | 0.75 | MMP1 (0.48) | MMP1FCER2MAPTHPGDSMN1; SMN2 | |
| SCHEMBL7120973 | 0.72 | MMP1 (0.60) | MMP1FCER2MAPTHPGDSMN1; SMN2 | |
| SCHEMBL7617896 | 0.68 | MMP1 (0.42) | MMP1FCER2MAPTHPGDSMN1; SMN2 | |
| SCHEMBL7424185 | 0.68 | MMP1 (0.42) | MMP1FCER2MAPTHPGDSMN1; SMN2 | |
| SCHEMBL28814774 | 0.68 | NPC1 (0.45) | MMP1FCER2MAPTHPGDSMN1; SMN2 | |
| SCHEMBL19369916 | 0.67 | MMP1 (0.45) | MMP1FCER2MAPTHPGDSMN1; SMN2 | |
| SCHEMBL24022309 | 0.67 | FBP1 (0.45) | MMP1FCER2MAPTHPGDSMN1; SMN2 | |
| SCHEMBL7247505 | 0.67 | MAOA (0.50) | MMP1FCER2MAPTHPGDSMN1; SMN2 | |
| SCHEMBL23879885 | 0.67 | HPGD (0.66) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7374649 | 0.66 | CYP2D6 (0.39) | MMP1HPGDMMP8RECQLUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357955-A1 | DRUG DELIVERY FROM STENTS | Biocompatibles UK Limited (GB) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002055121-A1 | DRUG DELIVERY FROM STENTS | BIOCOMPATIBLES UK LIMITED (GB) | 2002-07-18 | — | — | WO | disclosed |