Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.60 |
| ▸ | FCER2 | P06734 | 6/20 | 0.60 |
| ▸ | MMP2 | P08253 | 3/20 | 0.53 |
| ▸ | MMP3 | P08254 | 2/20 | 0.53 |
| ▸ | MMP7 | P09237 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.53 |
| ▸ | MMP14 | P50281 | 2/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.53 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23258231 | 0.82 | MMP1 (0.86) | MMP1FCER2MMP2MMP3MMP7 | |
| SCHEMBL20393464 | 0.81 | MMP1 (0.48) | MMP1FCER2MMP2MMP3MMP7 | |
| SCHEMBL15813401 | 0.77 | MMP1 (0.61) | MMP1FCER2MMP2MMP3MMP7 | |
| SCHEMBL3498528 | 0.77 | MMP1 (0.61) | MMP1FCER2MMP2MMP3MMP7 | |
| SCHEMBL7120970 | 0.72 | MMP1 (0.45) | MMP1FCER2MMP2MMP3MMP7 | |
| SCHEMBL7247505 | 0.72 | MAOA (0.50) | MMP1FCER2MMP2MMP3MMP7 | |
| SCHEMBL24022309 | 0.72 | FBP1 (0.45) | MMP1FCER2MMP2MMP3MMP7 | |
| SCHEMBL7424185 | 0.71 | MMP1 (0.42) | MMP1FCER2MMP2MMP3MMP7 | |
| SCHEMBL7617896 | 0.71 | MMP1 (0.42) | MMP1FCER2MMP2MMP3MMP7 | |
| Batimastat SCHEMBL4333 | 0.71 | MMP1 (1.00) | MMP1FCER2MMP2MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357955-A1 | DRUG DELIVERY FROM STENTS | Biocompatibles UK Limited (GB) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002055121-A1 | DRUG DELIVERY FROM STENTS | BIOCOMPATIBLES UK LIMITED (GB) | 2002-07-18 | — | — | WO | disclosed |