Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765682 | 0.97 | APP (0.38) | APPHTR2CHTR6IDO1SCN2A | |
| SCHEMBL15750399 | 0.93 | ALDH1A1 (0.44) | APPHTR2CHTR6IDO1SCN2A | |
| SCHEMBL31354848 | 0.93 | ALDH1A1 (0.44) | APPHTR2CHTR6IDO1SCN2A | |
| SCHEMBL12922776 | 0.85 | ALDH1A1 (0.43) | APPHTR2CHTR6SCN2AMGLL | |
| SCHEMBL21834385 | 0.84 | APP (0.37) | APPHTR2CHTR6IDO1SCN2A | |
| SCHEMBL14277972 | 0.83 | ALDH1A1 (0.42) | APPHTR2CHTR6MGLLCHRNB4 | |
| SCHEMBL16309386 | 0.83 | HTR2C (0.50) | APPHTR2CHTR6CYP1A2CYP2D6 | |
| SCHEMBL26366010 | 0.80 | APP (0.37) | APPHTR2CHTR6SCN2ACYP1A2 | |
| SCHEMBL30253469 | 0.79 | APP (0.55) | APPHTR2CHTR6SCN2AALDH1A1 | |
| SCHEMBL1651699 | 0.79 | APP (0.55) | APPHTR2CHTR6SCN2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105343-A1 | Benzofuran compounds | SHARP KABUSHIKI KAISHA (JP) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105343-A1 | Benzofuran compounds | BBOX1, DDO, OGFOD1 | APP 4010/4885HTR2C 1774/4885HTR6 2458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.