Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL744659 | 0.82 | PTGS2 (0.42) | ENPP2 | |
| SCHEMBL8510776 | 0.77 | LMNA (0.50) | LMNAENPP2ALDH1A1TSHRNT5E | |
| SCHEMBL8507889 | 0.77 | LMNA (0.50) | LMNAENPP2ALDH1A1TSHRNT5E | |
| SCHEMBL745572 | 0.76 | — | — | |
| SCHEMBL447639 | 0.76 | LMNA (0.65) | LMNAENPP2ALDH1A1TSHRNT5E | |
| SCHEMBL29990536 | 0.76 | LMNA (0.65) | LMNAENPP2ALDH1A1TSHRNT5E | |
| SCHEMBL525918 | 0.76 | LMNA (0.65) | LMNAENPP2ALDH1A1TSHRNT5E | |
| SCHEMBL3171676 | 0.76 | LMNA (0.65) | LMNAENPP2ALDH1A1TSHRNT5E | |
| SCHEMBL4780142 | 0.75 | ESR1 (0.48) | SMN1; SMN2NFKB1MAPT | |
| SCHEMBL9302694 | 0.73 | LMNA (0.62) | LMNAENPP2ALDH1A1TSHRNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358247-A2 | MELT POLYCARBONATE CATALYST SYSTEMS | GENERAL ELECTRIC COMPANY (US) | 2003-11-05 | — | — | EP | claimed |
| WO-2002055585-A2 | MELT POLYCARBONATE CATALYST SYSTEMS | GEN ELECTRIC (US) | 2002-07-18 | — | — | WO | claimed |
| CN-1247660-C | Melt polycarbonate catalyst systems | GEN ELECTRIC (US) | 2006-03-29 | — | — | CN | disclosed |
| CN-1541239-A | Melt Polycarbonate Catalyst System | ͨ�õ�����˾ | 2004-10-27 | — | — | CN | disclosed |