Oxirane

Oxirane

SCHEMBL7121149

C1CO1.CC(C)CCCCCC1(O)CCCCC1

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CETP P11597 1/20 0.32
LMNA P02545 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7112064 0.93 CETP (0.35) CETPLMNAOPRM1OPRD1OPRK1
SCHEMBL5545046 0.85 CETP (0.39) CETPLMNA
SCHEMBL17761461 0.84 LMNA (0.33) LMNA
SCHEMBL17607274 0.83 LMNA (0.39) LMNAOPRM1OPRD1OPRK1OPRL1
SCHEMBL17607217 0.83 LMNA (0.39) LMNAOPRM1OPRD1OPRK1OPRL1
SCHEMBL13814778 0.83 CETP (0.37) CETPLMNA
Oxirane SCHEMBL7112144 0.80 OPRM1 (0.41) OPRM1OPRD1OPRK1OPRL1
Oxirane SCHEMBL7112127 0.80 OPRM1 (0.41) OPRM1OPRD1OPRK1OPRL1
Oxirane SCHEMBL5318158 0.80 OPRM1 (0.41) OPRM1OPRD1OPRK1OPRL1
SCHEMBL1153604 0.77 CETP (0.32) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030009061-A1 Process for preparing an alkylcyclohexanol alkyleneoxide adduct INOUE YOSHIHISA (JP) 2003-01-09 US disclosed
US-6437194-B2 PURITY, LOW ALKYLPHENOL OR ALKYLPHENOL ALKYLENE OXIDE ADDUCT; HYDROGENATING ALKYLENE OXIDE ALKYLPHENOL ADDUCT; HYDROGENATING AN ALKYL PHENOL, REACTING ALKYLCYCLOHEXANOL; SOLVENT-FREE, WATER, AND SATURATED HYDROCARBON AS SOLVENTS MITSUI CHEMICALS, INC. (JP) 2002-08-20 US disclosed
US-20010051752-A1 PROCESS FOR PREPARING AN ALKYLCYCLOHEXANOL ALKYLENE OXIDE ADDUCT MITSUI CHEMICALS, INC. (JP) 2001-12-13 US disclosed
EP-0945421-A1 Alkylcyclohexanol-alkylene oxide adduct and preparation process thereof Mitsui Chemicals, Inc. (JP) 1999-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030009061-A1 Process for preparing an alkylcyclohexanol alkyleneoxide adduct APEX1, ATRIP, OTUB1 CETP 378/4885LMNA 1250/4885OPRM1 2666/4885
US-20010051752-A1 PROCESS FOR PREPARING AN ALKYLCYCLOHEXANOL ALKYLENE OXIDE ADDUCT APEX1, ATRIP, OTUB1 CETP 412/4885LMNA 1147/4885OPRM1 2432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.