Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GSDMD | P57764 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10926752 | 0.85 | POLB (0.37) | ALDH1A1ALDH2CA12CA1CA9 | |
| SCHEMBL3905585 | 0.83 | — | — | |
| SCHEMBL28912905 | 0.81 | ALDH1A1 (0.46) | ALDH1A1ALDH2LMNAL3MBTL1CA12 | |
| SCHEMBL134968 | 0.81 | ALDH1A1 (0.46) | ALDH1A1ALDH2LMNAL3MBTL1CA12 | |
| SCHEMBL9459638 | 0.81 | CA12 (0.45) | ALDH1A1ALDH2CA12CA1CA9 | |
| SCHEMBL5465384 | 0.79 | LMNA (0.52) | ALDH1A1ALDH2LMNAL3MBTL1CA12 | |
| SCHEMBL25163064 | 0.77 | LMNA (0.62) | ALDH1A1ALDH2LMNAL3MBTL1CA12 | |
| SCHEMBL1039434 | 0.77 | ALDH1A1 (0.43) | ALDH1A1ALDH2LMNAL3MBTL1CA12 | |
| SCHEMBL22271561 | 0.77 | ALDH1A1 (0.43) | ALDH1A1ALDH2LMNAL3MBTL1CA12 | |
| SCHEMBL8636679 | 0.77 | LMNA (0.50) | ALDH1A1ALDH2LMNAL3MBTL1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399051-B2 | KERATIN REDUCING AGENT | WELLA AKTIENGESELLSCHAFT (DE) | 2002-06-04 | — | — | US | claimed |
| EP-0969792-B1 | METHOD AND AGENTS FOR PERMANENTLY STYLING HAIR, WITH A BASE CONSISTING OF N,N-DISUBSTITUTED MERCAPTOACETAMIDES, AND METHOD FOR PRODUCING SAID MERCAPTOACETAMIDES | WELLA AG (DE) | 2003-11-12 | — | — | EP | disclosed |