Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121249 | 0.85 | ALDH1A1 (0.43) | POLBCA12CA1CA2CA9 | |
| SCHEMBL9459638 | 0.85 | CA12 (0.45) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL1232870 | 0.77 | ALDH1A1 (0.41) | POLBCA12CA1CA2CA9 | |
| SCHEMBL1387475 | 0.77 | POLB (0.39) | POLBCA12CA1CA2CA9 | |
| SCHEMBL10990860 | 0.77 | POLB (0.39) | POLBCA12CA1CA2CA9 | |
| SCHEMBL1387465 | 0.76 | ALDH1A1 (0.37) | POLBCA12CA1CA2CA9 | |
| SCHEMBL9647345 | 0.75 | LMNA (0.39) | POLBCA12CA1CA2CA9 | |
| SCHEMBL1387473 | 0.74 | POLB (0.38) | POLBCA12CA1CA2CA9 | |
| SCHEMBL1387466 | 0.74 | ALDH1A1 (0.39) | POLBCA12CA1CA2CA9 | |
| SCHEMBL3108822 | 0.72 | POLB (0.37) | POLBCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0128019-B1 | MULTIFUNCTIONAL ADDITIVES FOR FUNCTIONAL FLUIDS AND LUBRICANTS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1986-10-29 | — | — | EP | disclosed |
| EP-0128019-A2 | Multifunctional additives for functional fluids and lubricants | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1984-12-12 | — | — | EP | disclosed |
| US-4474674-A | THIOAMIDES | EXXON RESEARCH & ENGINEERING CO. (US) | 1984-10-02 | — | — | US | disclosed |