Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121715 | 0.77 | TUBB4A (0.44) | CA1CA2HTTALDH1A1LMNA | |
| SCHEMBL4983476 | 0.75 | CYP2D6 (0.51) | CA1CA2HTTALDH1A1LMNA | |
| SCHEMBL12180354 | 0.75 | CA1 (0.40) | CA1CA2HTTALDH1A1LMNA | |
| SCHEMBL15286196 | 0.74 | TUBB4A (0.41) | CA1CA2HTTALDH1A1LMNA | |
| SCHEMBL7121261 | 0.74 | TUBB4A (0.44) | CA1CA2HTTALDH1A1LMNA | |
| SCHEMBL4798350 | 0.73 | KMT2A (0.44) | CA1CA2ALDH1A1KMT2ACA12 | |
| SCHEMBL20550796 | 0.73 | ALDH1A1 (0.47) | HTTALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL7096179 | 0.73 | KMT2A (0.44) | ALDH1A1LMNAKMT2APAX8F2 | |
| SCHEMBL4801052 | 0.73 | ALDH1A1 (0.42) | CA1CA2ALDH1A1LMNAMAPT | |
| SCHEMBL4464950 | 0.71 | CYP2D6 (0.39) | CA1CA2HTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200412-B1 | IMIDAZOLE ANTIPROLIFERATIVE AGENTS | ABBOTT LAB (US) | 2003-11-12 | — | — | EP | disclosed |
| US-6201001-B1 | Imidazole antiproliferative agents | ABBOTT LABORATORIES | 2001-03-13 | — | — | US | disclosed |