SCHEMBL7121384

SCHEMBL7121384

NC(=O)c1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 4/20 0.86
NFE2L2 Q16236 1/20 0.86
ALDH1A1 P00352 4/20 0.70
L3MBTL1 Q9Y468 2/20 0.70
MAPT P10636 4/20 0.59
LMNA P02545 3/20 0.59
GRK6 P43250 1/20 0.56
ADORA2A P29274 1/20 0.55
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
POLB P06746 2/20 0.53
THRB P10828 2/20 0.53
MAPK1 P28482 2/20 0.53
RECQL P46063 1/20 0.53
NPC1 O15118 1/20 0.50
BCAT2 O15382 1/20 0.50
MAOA P21397 1/20 0.49
PKM P14618 1/20 0.49
MCL1 Q07820 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7829487 0.92 KEAP1 (0.73) KEAP1NFE2L2ALDH1A1L3MBTL1MAPT
SCHEMBL4930390 0.92 KEAP1 (1.00) KEAP1NFE2L2ALDH1A1L3MBTL1MAPT
SCHEMBL30268664 0.86 KEAP1 (0.70) KEAP1NFE2L2ALDH1A1L3MBTL1MAPT
SCHEMBL5866501 0.86 KEAP1 (0.69) KEAP1NFE2L2ALDH1A1L3MBTL1MAPT
SCHEMBL6989562 0.84 KEAP1 (0.84) KEAP1NFE2L2ALDH1A1L3MBTL1MAPT
SCHEMBL461660 0.82 ALDH1A1 (1.00) KEAP1NFE2L2ALDH1A1L3MBTL1MAPT
Anthraquinone SCHEMBL8941397 0.82 ALDH1A1 (1.00) KEAP1NFE2L2ALDH1A1L3MBTL1MAPT
Hydrochloric Acid SCHEMBL8675457 0.81 ALDH1A1 (0.96) KEAP1NFE2L2ALDH1A1L3MBTL1MAPT
SCHEMBL11147739 0.81 ALDH1A1 (0.70) KEAP1NFE2L2ALDH1A1L3MBTL1MAPT
SCHEMBL11287582 0.81 ALDH1A1 (0.70) KEAP1NFE2L2ALDH1A1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9777122-B2 Thickening compositions, and related materials and processes GENERAL ELECTRIC COMPANY (US) 2017-10-03 US claimed
US-20160297934-A1 THICKENING COMPOSITIONS, AND RELATED MATERIALS AND PROCESSES U.S. DEPARTMENT OF ENERGY 2016-10-13 US claimed
WO-2016164691-A1 THICKENING COMPOSITIONS, AND RELATED MATERIALS AND PROCESSES GENERAL ELECTRIC COMPANY (US) 2016-10-13 WO claimed
EP-0597287-B1 Process for the preparation of anthraquinones BASF AG (DE) 1996-04-10 EP claimed
EP-0597287-A1 Process for the preparation of anthraquinones BASF Aktiengesellschaft (DE) 1994-05-18 EP claimed
EP-0057382-B1 PROCESS FOR THE PREPARATION OF VAT DYES FROM THE WASTE PRODUCTS OF THE SYNTHESIS OF NITRO-ANTHRAQUINONE AND ANTHRAQUINONE SULFONIC ACID BAYER AG (DE) 1983-12-28 EP claimed
US-4369207-A PHOTOPOLYMERIZING TEIJIN LIMITED (JP) 1983-01-18 US claimed
JP-54160360-A None JP disclosed
JP-53130647-A None JP disclosed
US-10030483-B2 Carbon dioxide and hydrocarbon assisted enhanced oil recovery GENERAL ELECTRIC COMPANY (US) 2018-07-24 US disclosed
US-9777122-B2 Thickening compositions, and related materials and processes GENERAL ELECTRIC COMPANY (US) 2017-10-03 US disclosed
US-9777122-B2 Thickening compositions, and related materials and processes GENERAL ELECTRIC COMPANY (US) 2017-10-03 US disclosed
US-20170114269-A1 CARBON DIOXIDE AND HYDROCARBON ASSISTED ENHANCED OIL RECOVERY BAKER HUGHES, A GE COMPANY, LLC 2017-04-27 US disclosed
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed
EP-0057382-A2 Process for the preparation of vat dyes from the waste products of the synthesis of nitro-anthraquinone and anthraquinone sulfonic acid BAYER AG (DE) 1982-08-11 EP disclosed
EP-0047205-A2 Process for the preparation of alpha-benzamido-alpha'-halogen-1,1'-dianthrimides, alpha-benzamido-5' or 8'-halogen-1,1'-dianthrimides and their application as intermediates for vat dyes I.C.I. FRANCOLOR S.A. (FR) 1982-03-10 EP disclosed
JP-S54160360-A PREPARATION OF 1-AMINO-ANTHRAQUINONE NIPPON KAYAKU CO LTD 1979-12-19 JP disclosed
JP-S53130647-A PREPARATION OF 1-AMINOANTHRAQUINONE NIPPON KAYAKU CO LTD 1978-11-14 JP disclosed
US-3933821-A Direct production of 1,9-anthrapyrimidine-2-carboxylic acid-1, anthraquinonylamide in pigmentary form BASF AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed
US-3933821-A Direct production of 1,9-anthrapyrimidine-2-carboxylic acid-1, anthraquinonylamide in pigmentary form BASF AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed