Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.69 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 3/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | GRK6 | P43250 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829487 | 0.90 | KEAP1 (0.73) | KEAP1NFE2L2ALDH1A1MAPTLMNA | |
| SCHEMBL7121384 | 0.86 | KEAP1 (0.86) | KEAP1NFE2L2ALDH1A1MAPTLMNA | |
| SCHEMBL30268664 | 0.83 | KEAP1 (0.70) | KEAP1NFE2L2ALDH1A1MAPTLMNA | |
| SCHEMBL3605803 | 0.83 | KEAP1 (0.75) | KEAP1NFE2L2ALDH1A1MAPTLMNA | |
| SCHEMBL4930390 | 0.82 | KEAP1 (1.00) | KEAP1NFE2L2ALDH1A1MAPTLMNA | |
| SCHEMBL5866519 | 0.80 | ALDH1A1 (0.81) | ALDH1A1MAPTLMNAL3MBTL1NPC1 | |
| SCHEMBL3544809 | 0.78 | KEAP1 (0.58) | KEAP1NFE2L2ALDH1A1MAPTBCAT2 | |
| SCHEMBL2763213 | 0.76 | KEAP1 (0.56) | KEAP1NFE2L2ALDH1A1MAPTBCAT2 | |
| SCHEMBL10339858 | 0.76 | KEAP1 (0.56) | KEAP1NFE2L2ALDH1A1L3MBTL1BCAT2 | |
| SCHEMBL1512156 | 0.75 | KEAP1 (0.65) | KEAP1NFE2L2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349822-B1 | FLUORINATED AROMATIC COMPOUNDS AND THE USE OF THE SAME IN LIQUID CRYSTAL MIXTURES | MERCK PATENT GMBH (DE) | 2016-09-28 | — | — | EP | disclosed |
| US-7018685-B2 | Fluorinated aromatic compounds and the use of the same in liquid crystal mixtures | MERCK PATENT GMBH (DE) | 2006-03-28 | — | — | US | disclosed |
| US-20040124399-A1 | Fluorinated aromatic compounds and the use of the same in liquid crystal mixtures | MERCK PATENT GMBH (DE) | 2004-07-01 | — | — | US | disclosed |
| EP-1349822-A1 | FLUORINATED AROMATIC COMPOUNDS AND THE USE OF THE SAME IN LIQUID CRYSTAL MIXTURES | CLARIANT INTERNATIONAL LTD. (CH) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002055463-A1 | FLUORINATED AROMATIC COMPOUNDS AND THE USE OF THE SAME IN LIQUID CRYSTAL MIXTURES | CLARIANT INTERNATIONAL LTD. (CH) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040124399-A1 | Fluorinated aromatic compounds and the use of the same in liquid crystal mixtures | AFF1, AFF2, FLI1 | KEAP1 2750/4885NFE2L2 1534/4885ALDH1A1 2672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.