Sugi Predict

Sugi Predict / Compounds / SCHEMBL712191

SCHEMBL712191

SCHEMBL712191

O=c1cc[nH]c(=S)n1-c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.49
▸ HPGD P15428 4/20 0.49
▸ GAA P10253 3/20 0.49
▸ MEN1 O00255 2/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ GSK3B P49841 4/20 0.45
▸ GSK3A P49840 3/20 0.45
▸ MAPT P10636 4/20 0.45
▸ PDE7A Q13946 2/20 0.45
▸ PDE7B Q9NP56 2/20 0.45
▸ RECQL P46063 1/20 0.45
▸ NPSR1 Q6W5P4 1/20 0.42
▸ RXFP1 Q9HBX9 1/20 0.42
▸ POLB P06746 1/20 0.41
▸ LOXL3 P58215 1/20 0.40
▸ LOXL2 Q9Y4K0 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45000 0.80 GSK3A (0.54) ALDH1A1HPGDGAAMEN1KMT2A
SCHEMBL3536651 0.80 ALDH1A1 (0.52) ALDH1A1HPGDGAAMEN1KMT2A
SCHEMBL28989105 0.73 TDP1 (0.44) ALDH1A1HPGDGAAMEN1KMT2A
SCHEMBL4715222 0.70 JAK2 (0.44) ALDH1A1HPGDGAAMEN1KMT2A
SCHEMBL11042133 0.69 ALDH1A1 (0.61) ALDH1A1HPGDGAAMEN1KMT2A
SCHEMBL2284398 0.69 ALDH1A1 (0.53) ALDH1A1HPGDGAAMEN1KMT2A
SCHEMBL11619693 0.68 GSK3B (0.72) ALDH1A1HPGDGAAMEN1KMT2A
SCHEMBL11618148 0.68 ALDH1A1 (0.59) ALDH1A1HPGDGAAMEN1KMT2A
SCHEMBL5012600 0.68 GAA (0.52) ALDH1A1HPGDGAAMEN1KMT2A
SCHEMBL6065591 0.67 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107817306-A Method for simultaneously detecting 64 veterinary drug residues in aquatic product 中山出入境检验检疫局检验检疫技术中心 2018-03-20 — — CN claimed
US-8252925-B2 Method for the production of 3-phenyl(thio)uracils and dithiouracils BASF AKTIENGESELLSCHAFT (DE) 2012-08-28 — — US claimed
US-7737275-B2 Method for producing 3-phenyl(thio)uracils and 3-phenyldithiouracils BASF AKTIENGESELLSCHAFT (DE) 2010-06-15 — — US claimed
US-20080033174-A1 Method for the Production of 3-Phenyl (Thio) Uracils and Dithiouracils BASF AKTIENGESELLSCHAFT (DE) 2008-02-07 — — US claimed
EP-1692115-B1 METHOD FOR PRODUCING 3-PHENYL(THIO)URACILS AND 3-PHENYLDITHIOURACILS BASF AG (DE) 2007-12-19 — — EP claimed
EP-1773787-A1 METHOD FOR THE PRODUCTION OF 3-PHENYL(THIO)URACILS AND DITHIOURACILS BASF AKTIENGESELLSCHAFT (DE) 2007-04-18 — — EP claimed
US-20060293520-A1 Mehtod for producing 3-phenyl(thio)uracils and 3-phenyldithiouracils BASF AKTIENGESELLSCHAFT (DE) 2006-12-28 — — US claimed
EP-1692115-A1 METHOD FOR PRODUCING 3-PHENYL(THIO)URACILS AND 3-PHENYLDITHIOURACILS BASF AKTIENGESELLSCHAFT (DE) 2006-08-23 — — EP claimed
WO-2006010474-A1 METHOD FOR THE PRODUCTION OF 3-PHENYL(THIO)URACILS AND DITHIOURACILS BASF AKTIENGESELLSCHAFT (DE) 2006-02-02 — — WO claimed
WO-2005054208-A1 METHOD FOR PRODUCING 3-PHENYL(THIO)URACILS AND 3-PHENYLDITHIOURACILS BASF AKTIENGESELLSCHAFT (DE) 2005-06-16 — — WO claimed
US-20230273456-A1 OPTICALLY ACTIVE DEVICES JOHNSON & JOHNSON SURGICAL VISION INC (US) 2023-08-31 — — US disclosed
US-20230273456-A1 OPTICALLY ACTIVE DEVICES JOHNSON & JOHNSON SURGICAL VISION INC (US) 2023-08-31 — — US disclosed
CN-112218860-A Substituted phenylthiouracils, their salts and their use as herbicides 先正达农作物保护股份公司 2021-01-12 — — CN disclosed
CN-112218860-A Substituted phenylthiouracils, their salts and their use as herbicides 先正达农作物保护股份公司 2021-01-12 — — CN disclosed
CN-112218860-A Substituted phenylthiouracils, their salts and their use as herbicides 先正达农作物保护股份公司 2021-01-12 — — CN disclosed
WO-2005054208-A1 METHOD FOR PRODUCING 3-PHENYL(THIO)URACILS AND 3-PHENYLDITHIOURACILS BASF AKTIENGESELLSCHAFT (DE) 2005-06-16 — — WO disclosed
WO-2005054208-A1 METHOD FOR PRODUCING 3-PHENYL(THIO)URACILS AND 3-PHENYLDITHIOURACILS BASF AKTIENGESELLSCHAFT (DE) 2005-06-16 — — WO disclosed
CN-1360500-A Use of sulfamate derivatives for the treatment of impulse control disorders UNIV CINCINNATI (US) 2002-07-24 — — CN disclosed
WO-2000021936-A1 URACIL HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-04-20 — — WO disclosed
US-4088751-A SHAVING CREAM, SHAMPOO, LOTION, 2-THIO-4-OXYPYRIMIDINE OR THIOHYDANTOIN AND HYDROGEN PEROXIDE, EXOTHERMIC REDOX REACTION COLGATE-PALMOLIVE COMPANY (US) 1978-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060293520-A1 Mehtod for producing 3-phenyl(thio)uracils and 3-phenyldithiouracils HPRT1, TH, METTL3 ALDH1A1 353/4885HPGD 1550/4885GAA 3726/4885
US-20230273456-A1 OPTICALLY ACTIVE DEVICES PDE6C, PDE6D, PDE6A ALDH1A1 277/4885HPGD 65/4885GAA 1954/4885
US-20080033174-A1 Method for the Production of 3-Phenyl (Thio) Uracils and Dithiouracils TPMT, TYMP, TYMS ALDH1A1 233/4885HPGD 505/4885GAA 1862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.