Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GNA15 | P30679 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5393174 | 0.78 | MTNR1B (0.46) | GAAMAPTTHRBALDH1A1LMNA | |
| SCHEMBL5389109 | 0.77 | CYP19A1 (0.39) | GAAMAPTTHRBTDP1ALDH1A1 | |
| SCHEMBL5859473 | 0.77 | RNF4 (0.41) | GAATP53MAPTTHRBTDP1 | |
| SCHEMBL7122041 | 0.75 | THRB (0.51) | FFAR1FFAR4BCHEACHECA1 | |
| SCHEMBL5859386 | 0.74 | FFAR1 (0.64) | FFAR1FFAR4BCHEACHECA1 | |
| SCHEMBL5382492 | 0.73 | MEN1 (0.46) | GAAMAPTALDH1A1LMNAHTT | |
| SCHEMBL5382504 | 0.73 | BACE1 (0.42) | GAATHRBTDP1ALDH1A1LMNA | |
| SCHEMBL5385584 | 0.73 | ICAM1 (0.35) | ACHEGAAMAPTTHRBALDH1A1 | |
| SCHEMBL5388204 | 0.73 | NR4A1 (0.39) | ACHEGAAMAPTTHRBLMNA | |
| SCHEMBL5455782 | 0.71 | THRB (0.45) | THRBTDP1ALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358175-A2 | PHENOXY SUBSTITUTED BENZOCONDENSED HETEROARYL DERIVATIVES AS THYROID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002062780-A2 | PHENOXY SUBSTITUTED BENZOCONDENSED HETEROARYL DERIVATIVES AS THYROID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2002-08-15 | — | — | WO | disclosed |