Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.64 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | GNA15 | P30679 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122041 | 0.81 | THRB (0.51) | FFAR1PPARGPPARAFFAR4CA1 | |
| SCHEMBL5381972 | 0.79 | MTNR1B (0.50) | THRBRORCPTGS1THRA | |
| SCHEMBL11804605 | 0.79 | FFAR1 (0.71) | FFAR1PPARGPPARAFFAR4CA1 | |
| SCHEMBL17455196 | 0.78 | FFAR1 (1.00) | FFAR1FFAR4HIF1APTGS1GNA15 | |
| SCHEMBL30924433 | 0.78 | FFAR1 (1.00) | FFAR1FFAR4HIF1APTGS1GNA15 | |
| SCHEMBL5858200 | 0.76 | PTGS1 (0.46) | THRBPTGS1THRA | |
| SCHEMBL5859476 | 0.76 | RNF4 (0.46) | FFAR1THRBRORCPTGS1THRA | |
| SCHEMBL7122037 | 0.74 | FFAR1 (0.43) | FFAR1PPARGPPARAFFAR4CA1 | |
| SCHEMBL5386428 | 0.72 | KMT2A (0.47) | THRBPTGS1THRA | |
| SCHEMBL6912094 | 0.72 | THRA (0.45) | THRBPTGS1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144909-B2 | Phenoxy substituted benzocondensed heteroaryl derivatives as thyroid receptor ligands | KARO BIO AB (SE) | 2006-12-05 | — | — | US | disclosed |
| US-20040116387-A1 | Phenoxy substituted benzocondensed heteroaryl derivatives as thyroid receptor ligands | KARO BIO AB (SE) | 2004-06-17 | — | — | US | disclosed |