Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404479 | 0.82 | PDK2 (0.30) | PDK2 | |
| SCHEMBL6924471 | 0.78 | SIGMAR1 (0.43) | — | |
| SCHEMBL28618972 | 0.75 | PDK2 (0.36) | PDK2 | |
| SCHEMBL19454302 | 0.73 | PDK2 (0.33) | PDK2 | |
| SCHEMBL2665687 | 0.73 | KIF11 (0.41) | — | |
| SCHEMBL29575429 | 0.73 | KIF11 (0.41) | — | |
| SCHEMBL14803820 | 0.69 | PDK2 (0.38) | PDK2 | |
| SCHEMBL19454304 | 0.69 | CYP1A2 (0.35) | PDK2 | |
| SCHEMBL15614862 | 0.69 | AHR (0.34) | PDK2 | |
| SCHEMBL10260726 | 0.69 | PDK2 (0.35) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015577-B1 | PROCESS FOR PRODUCING 1,1,3,3-TETRAFLUORO-1,3-DIHYDRO-ISOBENZOFURAN | NIHON NOHYAKU CO., LTD. (JP) | 1982-02-03 | — | — | EP | claimed |
| US-4283344-A | Process for producing 1,1,3,3-tetrafluoro-1,3-dihydro-isobenzofuran | NIHON NOHYAKU CO., LTD. (JP) | 1981-08-11 | — | — | US | claimed |
| EP-0015577-A1 | Process for producing 1,1,3,3-tetrafluoro-1,3-dihydro-isobenzofuran | NIHON NOHYAKU CO., LTD. (JP) | 1980-09-17 | — | — | EP | claimed |
| JP-55129243-A | — | — | None | — | — | JP | disclosed |
| JP-55129242-A | — | — | None | — | — | JP | disclosed |
| JP-55129278-A | — | — | None | — | — | JP | disclosed |
| US-11917901-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-11917901-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-11005050-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| EP-3424936-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-04-07 | — | — | EP | disclosed |
| US-20200216605-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-07-09 | — | — | US | disclosed |
| US-4283344-A | Process for producing 1,1,3,3-tetrafluoro-1,3-dihydro-isobenzofuran | NIHON NOHYAKU CO., LTD. (JP) | 1981-08-11 | — | — | US | disclosed |
| US-4283344-A | Process for producing 1,1,3,3-tetrafluoro-1,3-dihydro-isobenzofuran | NIHON NOHYAKU CO., LTD. (JP) | 1981-08-11 | — | — | US | disclosed |
| EP-0018481-A1 | Process for producing alpha, alpha, alpha-trifluoro-o-toluic fluoride | NIHON NOHYAKU CO., LTD. (JP) | 1980-11-12 | — | — | EP | disclosed |
| JP-S55129242-A | PREPARATION OF ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLUOYL FLUORIDE | NIPPON NOHYAKU CO LTD | 1980-10-06 | — | — | JP | disclosed |
| JP-S55129243-A | PREPARATION OF ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLUOYL FLUORIDE | NIPPON NOHYAKU CO LTD | 1980-10-06 | — | — | JP | disclosed |
| JP-S55129278-A | PREPARATION OF 1,1,3,3-TETRAFLUORO-1,3-DIHYDRO ISOBENZOFURAN | NIPPON NOHYAKU CO LTD | 1980-10-06 | — | — | JP | disclosed |
| EP-0015577-A1 | Process for producing 1,1,3,3-tetrafluoro-1,3-dihydro-isobenzofuran | NIHON NOHYAKU CO., LTD. (JP) | 1980-09-17 | — | — | EP | disclosed |
| EP-0015577-A1 | Process for producing 1,1,3,3-tetrafluoro-1,3-dihydro-isobenzofuran | NIHON NOHYAKU CO., LTD. (JP) | 1980-09-17 | — | — | EP | disclosed |
| EP-0015577-A1 | Process for producing 1,1,3,3-tetrafluoro-1,3-dihydro-isobenzofuran | NIHON NOHYAKU CO., LTD. (JP) | 1980-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11005050-B2 | Metal complexes | SOD1, AP1M1, AP3M1 | PDK2 2330/4885 |
| US-11917901-B2 | Metal complexes | MCOLN2, MCOLN1, AP1M1 | PDK2 3019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.