Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27168219 | 0.85 | TDP1 (0.51) | NPC1MAPTLMNATSHRNPSR1 | |
| SCHEMBL25375164 | 0.83 | ALDH2 (0.44) | NPC1MAPTTSHRTDP1MEN1 | |
| SCHEMBL14457411 | 0.83 | NPC1 (0.39) | NPC1MAPTLMNATSHRNPSR1 | |
| SCHEMBL3222585 | 0.82 | NPC1 (0.60) | NPC1MAPTLMNATSHRNPSR1 | |
| SCHEMBL30056432 | 0.82 | NPC1 (0.60) | NPC1MAPTLMNATSHRNPSR1 | |
| SCHEMBL7233158 | 0.82 | LMNA (0.45) | NPC1MAPTLMNATSHRNPSR1 | |
| SCHEMBL13366375 | 0.81 | NPC1 (0.39) | NPC1MAPTLMNATSHRNPSR1 | |
| SCHEMBL7128120 | 0.81 | ADRB2 (0.42) | NPC1MAPTLMNATSHRNPSR1 | |
| SCHEMBL28965238 | 0.81 | LMNA (0.47) | NPC1MAPTLMNATSHRNPSR1 | |
| SCHEMBL819248 | 0.80 | NPC1 (0.35) | NPC1MAPTLMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030225192-A1 | Mxitures of 2-(2-hydroxy-4(3-butoxy-2-hydroxypropyloxy)-phenyl )-4,6-bis(2,4-dimethylphenyl)-1,3,5-triazine and hindered amine light stabilizers, used for stabilization of curable polycarbonates | BIRBAUM JEAN-LUC (CH) | 2003-12-04 | — | — | US | disclosed |
| US-6608122-B1 | O-Hydroxyphenyl-s-triazines in combination with sterically hindered amines of the polyalkylpiperidine type | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-08-19 | — | — | US | disclosed |
| US-6355708-B2 | USEFUL IN STABILIZING POLYMERS AND OTHER MATERIALS FROM DEGRADATION BY ENVIRONMENTAL FORCES SUCH AS ACTINIC RADIATION (ULTRAVIOLET LIGHT), OXIDATION, MOISTURE, ATMOSPHERIC POLLUTANTS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-03-12 | — | — | US | disclosed |
| US-20010031866-A1 | Novel trisaryl-1,3,5-triazine ultraviolet light absorbers | GUPTA RAM BABOO (US) | 2001-10-18 | — | — | US | disclosed |
| US-6242597-B1 | STABILIZERS WITH A BONDABLE GROUP HAVING AN ACTIVE (ACIDIC) HYDROGEN; MIGRATION BETWEEN POLYMER LAYERS IS REDUCED | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-06-05 | — | — | US | disclosed |
| US-6187919-B1 | ULTRAVIOLET ABSORBERS | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-02-13 | — | — | US | disclosed |
| EP-1032563-A1 | TRISARYL-1,3,5-TRIAZINE ULTRAVIOLET LIGHT ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999026934-A1 | TRISARYL-1,3,5-TRIAZINE ULTRAVIOLET LIGHT ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 1999-06-03 | — | — | WO | disclosed |
| US-5736597-A | USING O-HYDROXYPHENYL-S-TRIAZINE AND STERIC HINDERED AMINE OF THE POLYALKYLPIPERIDINE TYPE | CIBA-GEIGY CORPORATION (US) | 1998-04-07 | — | — | US | disclosed |
| EP-0434608-B1 | Stabilized organic material | CIBA GEIGY AG (CH) | 1997-04-02 | — | — | EP | disclosed |
| EP-0434608-A1 | Stabilized organic material | CIBA-GEIGY AG (CH) | 1991-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225192-A1 | Mxitures of 2-(2-hydroxy-4(3-butoxy-2-hydroxypropyloxy)-phenyl )-4,6-bis(2,4-dimethylphenyl)-1,3,5-triazine and hindered amine light stabilizers, used for stabilization of curable polycarbonates | SIGMAR1, H1-2, H1-5 | NPC1 3864/4885MAPT 2018/4885LMNA 1846/4885 |
| US-20010031866-A1 | Novel trisaryl-1,3,5-triazine ultraviolet light absorbers | ERCC5, XRCC5, ERCC1 | NPC1 2328/4885MAPT 178/4885LMNA 1362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.