SCHEMBL7122913

SCHEMBL7122913

O=C(O)CC(COCc1ccccc1)(CC(=O)O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.49
POLB P06746 1/20 0.49
TSHR P16473 1/20 0.47
KMT2A Q03164 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
ALDH1A1 P00352 5/20 0.42
FFAR1 O14842 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MEN1 O00255 1/20 0.40
CA1 P00915 1/20 0.40
PPARA Q07869 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3547434 0.89 KDM4E (0.55) KDM4EPOLBTSHRKMT2ATDP1
SCHEMBL8839506 0.78 KDM4E (0.55) KDM4EPOLBTSHRKMT2ATDP1
Citric Acid SCHEMBL15361754 0.77 ALDH1A1 (0.54) KDM4EPOLBTSHRKMT2ATDP1
SCHEMBL1691754 0.77 KDM4E (0.53) KDM4EPOLBTSHRKMT2ATDP1
SCHEMBL7289855 0.76 HIF1A (0.53) KDM4EKMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL9565522 0.75 ALDH1A1 (0.53) KDM4EPOLBTSHRKMT2ATDP1
SCHEMBL3545416 0.75 KDM4E (0.51) KDM4EPOLBTSHRKMT2ATDP1
SCHEMBL31397663 0.75 KDM4E (0.51) KDM4EPOLBTSHRKMT2ATDP1
SCHEMBL15012407 0.74 KDM4E (0.50) KDM4EPOLBTSHRKMT2ATDP1
SCHEMBL15012155 0.74 KDM4E (0.50) KDM4EPOLBTSHRKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030186823-A1 Novel compositions of material, especially lubricants and pressure transmitting means, the production and use thereof FUCHS PETROLUB SE (DE) 2003-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186823-A1 Novel compositions of material, especially lubricants and pressure transmitting means, the production and use thereof SLC27A2, SLC27A1, ELOVL1 KDM4E 4757/4885POLB 1581/4885TSHR 4744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.