SCHEMBL7123361

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7116736	0.87	SIRT1 (0.42)	SIRT1HTR6SLC6A4MEN1KMT2A
	SCHEMBL7113422	0.87	BCHE (0.38)	MEN1KMT2ALMNAHTR2ASMN1; SMN2
	SCHEMBL7115575	0.84	SIRT1 (0.42)	SIRT1HTR6SLC6A4OPRM1OPRD1
	SCHEMBL7120331	0.83	SIRT1 (0.42)	SIRT1HTR6OPRM1OPRD1OPRK1
	SCHEMBL7125974	0.82	SIRT1 (0.44)	SIRT1MEN1KMT2AMAPTALDH1A1
	SCHEMBL7552947	0.78	SIRT1 (0.40)	SIRT1MEN1KMT2AMAPTLMNA
	SCHEMBL7123048	0.78	LMNA (0.41)	HTR6SLC6A4MEN1KMT2AMAPT
	SCHEMBL7116504	0.74	TSHR (0.42)	MAPTALDH1A1TSHR
	SCHEMBL7121233	0.73	SIRT1 (0.42)	SIRT1HTR6SLC6A4OPRM1OPRD1
	SCHEMBL7114914	0.73	SIRT1 (0.46)	SIRT1MEN1KMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.