SCHEMBL7120331

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7552947	0.94	SIRT1 (0.40)	SIRT1LMNAMEN1KMT2AMAPT
	SCHEMBL7124010	0.86	SIRT1 (0.45)	SIRT1LMNAMEN1KMT2AMAPT
	SCHEMBL7122174	0.85	GHSR (0.39)	LMNAMEN1KMT2AHTR2AHTR2C
	SCHEMBL7116744	0.85	SIRT1 (0.46)	SIRT1LMNAMEN1KMT2AMAPT
	SCHEMBL7123361	0.83	SIRT1 (0.40)	SIRT1OPRM1OPRD1OPRK1OPRL1
	SCHEMBL7114914	0.82	SIRT1 (0.46)	SIRT1LMNAMEN1KMT2AMAPT
	SCHEMBL7118632	0.80	SIRT1 (0.44)	SIRT1LMNAMEN1KMT2AMAPT
	SCHEMBL7114058	0.80	LMNA (0.36)	SIRT1OPRM1OPRD1OPRK1OPRL1
	SCHEMBL7118690	0.74	MEN1 (0.40)	SIRT1LMNAMEN1KMT2AMAPT
	SCHEMBL7115575	0.73	SIRT1 (0.42)	SIRT1OPRM1OPRD1OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.