Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6644469 | 0.92 | HTR2C (0.38) | ENPP2HTR2CALDH1A1LMNATHRB | |
| SCHEMBL6648472 | 0.91 | HTR2C (0.37) | ENPP2HTR2CALDH1A1LMNATHRB | |
| SCHEMBL6647263 | 0.89 | HTR2C (0.36) | ENPP2HTR2CALDH1A1LMNAPANK3 | |
| SCHEMBL5075675 | 0.88 | ENPP2 (0.43) | ENPP2HTR2CALDH1A1LMNATSHR | |
| SCHEMBL5077591 | 0.87 | ALDH1A1 (0.41) | ENPP2HTR2CALDH1A1LMNA | |
| SCHEMBL5082046 | 0.86 | CYP3A4 (0.45) | ENPP2HTR2CALDH1A1LMNATSHR | |
| SCHEMBL6011375 | 0.86 | SMN1; SMN2 (0.43) | ENPP2HTR2CALDH1A1PANK3 | |
| SCHEMBL5078920 | 0.85 | ENPP2 (0.40) | ENPP2HTR2CALDH1A1LMNATSHR | |
| SCHEMBL5078917 | 0.85 | HTR2C (0.40) | ENPP2HTR2CALDH1A1LMNATSHR | |
| SCHEMBL5075648 | 0.85 | HTR6 (0.46) | HTR2CTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112251-B1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-05-07 | — | — | EP | claimed |