SCHEMBL712374

SCHEMBL712374

Cc1ccc(CCCCCCC(=O)O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.69
RXFP1 Q9HBX9 1/20 0.69
FFAR1 O14842 2/20 0.59
HSD17B10 Q99714 1/20 0.58
HDAC3 O15379 1/20 0.57
MAPK1 P28482 1/20 0.57
ADRA1A P35348 1/20 0.57
HDAC4 P56524 1/20 0.57
SLC6A3 Q01959 1/20 0.57
HDAC1 Q13547 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
HDAC7 Q8WUI4 1/20 0.57
HDAC2 Q92769 1/20 0.57
HDAC10 Q969S8 1/20 0.57
HDAC11 Q96DB2 1/20 0.57
HDAC8 Q9BY41 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
HDAC9 Q9UKV0 1/20 0.57
HDAC5 Q9UQL6 1/20 0.57
RXRA P19793 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8002906 1.00 MAPT (0.69) MAPTRXFP1FFAR1HSD17B10HDAC3
SCHEMBL10956007 1.00 MAPT (0.69) MAPTRXFP1FFAR1HSD17B10HDAC3
SCHEMBL4189855 1.00 MAPT (0.69) MAPTRXFP1FFAR1HSD17B10HDAC3
SCHEMBL878982 1.00 MAPT (0.69) MAPTRXFP1FFAR1HSD17B10HDAC3
SCHEMBL26313655 1.00 MAPT (0.69) MAPTRXFP1FFAR1HSD17B10HDAC3
SCHEMBL25167628 1.00 MAPT (0.69) MAPTRXFP1FFAR1HSD17B10HDAC3
SCHEMBL11295813 1.00 MAPT (0.69) MAPTRXFP1FFAR1HSD17B10HDAC3
SCHEMBL11291327 1.00 MAPT (0.69) MAPTRXFP1FFAR1HSD17B10HDAC3
SCHEMBL1066202 0.98 MAPT (0.66) MAPTRXFP1FFAR1HSD17B10HDAC3
SCHEMBL1139126 0.98 MAPT (0.66) MAPTRXFP1FFAR1HSD17B10HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190240235-A1 LIPOBALANCED LONG CHAIN TESTOSTERONE ESTERS FOR ORAL DELIVERY LIPOCINE INC. (US) 2019-08-08 US disclosed
US-20170020893-A1 LIPOBALANCED LONG CHAIN TESTOSTERONE PRODRUGS FOR ORAL DELIVERY LIPOCINE INC. (US) 2017-01-26 US disclosed
US-20170020893-A1 LIPOBALANCED LONG CHAIN TESTOSTERONE PRODRUGS FOR ORAL DELIVERY LIPOCINE INC. (US) 2017-01-26 US disclosed
US-20140288039-A1 LIPOBALANCED LONG CHAIN TESTOSTERONE PRODRUGS FOR ORAL DELIVERY LIPOCINE INC. (US) 2014-09-25 US disclosed
US-20140288039-A1 LIPOBALANCED LONG CHAIN TESTOSTERONE PRODRUGS FOR ORAL DELIVERY LIPOCINE INC. (US) 2014-09-25 US disclosed
US-8124778-B2 Tricyclic inhibitors of fatty acid amide hydrolase THE SCRIPPS RESEARCH INSTITUTE (US) 2012-02-28 US disclosed
US-8124778-B2 Tricyclic inhibitors of fatty acid amide hydrolase THE SCRIPPS RESEARCH INSTITUTE (US) 2012-02-28 US disclosed
US-8124778-B2 Tricyclic inhibitors of fatty acid amide hydrolase THE SCRIPPS RESEARCH INSTITUTE (US) 2012-02-28 US disclosed
US-20100216750-A1 TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE THE SCRIPPS RESEARCH INSTITUTE (US) 2010-08-26 US disclosed
US-20100216750-A1 TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE THE SCRIPPS RESEARCH INSTITUTE (US) 2010-08-26 US disclosed
US-20100216750-A1 TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE THE SCRIPPS RESEARCH INSTITUTE (US) 2010-08-26 US disclosed
EP-2161997-A1 TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE Boger, Dale L. (US) 2010-03-17 EP disclosed
WO-2008150492-A1 TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE THE SCRIPPS RESEARCH INSTITUTE (US) 2008-12-11 WO disclosed
WO-2008150492-A1 TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE THE SCRIPPS RESEARCH INSTITUTE (US) 2008-12-11 WO disclosed
US-7459517-B2 Polyhydroxyalkanoate, process for preparing the same, and resin composition containing the polyhydroxyalkanoate CANON KABUSHIKI KAISHA (JP) 2008-12-02 US disclosed
US-20060079662-A1 High thermal stability, charge stablity, a high charge amount, improved dispersibility and biodegradability together; for resin moldings, and binders and charge controlling agents for toners used in the electrophotography CANON KABUSHIKI KAISHA (JP) 2006-04-13 US disclosed
WO-2004037889-A1 POLYHYDROXYALKANOATE, PROCESS FOR PREPARING THE SAME, AND RESIN COMPOSITION CONTAINING THE POLYHYDROXYALKANOATE CANON KABUSHIKI KAISHA (JP) 2004-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140288039-A1 LIPOBALANCED LONG CHAIN TESTOSTERONE PRODRUGS FOR ORAL DELIVERY SHBG, CYP17A1, CYP19A1 MAPT 3508/4885RXFP1 2799/4885FFAR1 214/4885
US-20100216750-A1 TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE FADS1, FAAH, SCD MAPT 3956/4885RXFP1 2442/4885FFAR1 30/4885
US-20190240235-A1 LIPOBALANCED LONG CHAIN TESTOSTERONE ESTERS FOR ORAL DELIVERY SHBG, CYP17A1, LIPE MAPT 3511/4885RXFP1 2748/4885FFAR1 200/4885
US-20170020893-A1 LIPOBALANCED LONG CHAIN TESTOSTERONE PRODRUGS FOR ORAL DELIVERY SHBG, CYP17A1, CYP19A1 MAPT 3508/4885RXFP1 2799/4885FFAR1 214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.