Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7123916

N.O=c1[nH]cc([N+](=O)O)c(=O)[nH]1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.48
DPYD Q12882 5/20 0.43
MAPT P10636 3/20 0.43
ALDH1A1 P00352 3/20 0.43
LMNA P02545 3/20 0.43
ATAD2 Q6PL18 1/20 0.43
CYP19A1 P11511 1/20 0.43
TSHR P16473 1/20 0.43
THPO P40225 1/20 0.43
MTOR P42345 1/20 0.43
HTT P42858 1/20 0.43
HBB P68871 1/20 0.43
PMP22 Q01453 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KDM4C Q9H3R0 1/20 0.35
KLF10 Q13118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL7123914 0.79 LMNA (0.45) GAADPYDMAPTALDH1A1LMNA
SCHEMBL190925 0.77 LMNA (0.47) GAADPYDMAPTALDH1A1LMNA
Hydrazine SCHEMBL7121815 0.73 LMNA (0.44) GAADPYDMAPTALDH1A1LMNA
Guanidine SCHEMBL7115879 0.72 LMNA (0.41) GAADPYDMAPTALDH1A1LMNA
Thymine SCHEMBL31471702 0.68 ATAD2 (0.73) GAADPYDMAPTALDH1A1LMNA
SCHEMBL7225377 0.66 KDM4E (0.40) GAADPYDMAPTALDH1A1LMNA
SCHEMBL48366 0.66
Fluorouracil SCHEMBL27850530 0.64 MAPT (0.95) GAADPYDMAPTALDH1A1LMNA
SCHEMBL29420246 0.64 DPYD (0.50) GAADPYDMAPTALDH1A1LMNA
Thymine SCHEMBL646138 0.64 ATAD2 (0.95) GAADPYDMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6589375-B2 Using basic copper nitrate as oxidizer TALLEY DEFENSE SYSTEMS, INC. 2003-07-08 US claimed
US-20030094225-A1 LOW SOLIDS GAS GENERANT HAVING A LOW FLAME TEMPERATURE TALLY DEFENSE SYSTEMS, INC. 2003-05-22 US claimed
US-6589375-B2 Using basic copper nitrate as oxidizer TALLEY DEFENSE SYSTEMS, INC. 2003-07-08 US disclosed
US-6589375-B2 Using basic copper nitrate as oxidizer TALLEY DEFENSE SYSTEMS, INC. 2003-07-08 US disclosed
US-20030094225-A1 LOW SOLIDS GAS GENERANT HAVING A LOW FLAME TEMPERATURE TALLY DEFENSE SYSTEMS, INC. 2003-05-22 US disclosed
US-20030094225-A1 LOW SOLIDS GAS GENERANT HAVING A LOW FLAME TEMPERATURE TALLY DEFENSE SYSTEMS, INC. 2003-05-22 US disclosed