Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.64 |
| ▸ | CASP7 | P55210 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119082 | 0.86 | RAB9A (0.59) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7120049 | 0.86 | MAPT (0.60) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7118157 | 0.85 | RAB9A (0.67) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL7761958 | 0.83 | MEN1 (0.56) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL10943445 | 0.82 | RAB9A (0.88) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL5879030 | 0.82 | RAB9A (0.88) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL31680576 | 0.78 | RAB9A (0.81) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL5925493 | 0.77 | RAB9A (0.61) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL9422337 | 0.77 | SMN1; SMN2 (0.73) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL23092251 | 0.77 | RAB9A (0.68) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212074-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-13 | — | — | US | disclosed |
| WO-2001082924-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212074-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A3, SLC34A1 | ALDH1A1 3126/4885MAPT 3743/4885MEN1 2716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.