Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119082 | 0.96 | RAB9A (0.59) | MEN1KMT2ASMN1; SMN2NPC1GAA | |
| SCHEMBL7114636 | 0.84 | SMN1; SMN2 (0.69) | MEN1KMT2ASMN1; SMN2NPC1GAA | |
| SCHEMBL6707294 | 0.84 | RAB9A (0.76) | MEN1KMT2ASMN1; SMN2NPC1GAA | |
| SCHEMBL7124123 | 0.83 | ALDH1A1 (0.64) | MEN1KMT2ASMN1; SMN2NPC1GAA | |
| SCHEMBL7113128 | 0.83 | TAS1R3 (0.64) | MEN1KMT2ASMN1; SMN2NPC1GAA | |
| SCHEMBL7118768 | 0.83 | RAB9A (0.61) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7116292 | 0.83 | P2RX1 (0.56) | MEN1KMT2ASMN1; SMN2NPC1HTT | |
| SCHEMBL7120049 | 0.81 | MAPT (0.60) | MEN1KMT2ASMN1; SMN2NPC1GAA | |
| SCHEMBL7763476 | 0.81 | SMN1; SMN2 (0.64) | MEN1KMT2ASMN1; SMN2NPC1GAA | |
| SCHEMBL4111911 | 0.80 | TRPV1 (0.75) | MEN1KMT2ASMN1; SMN2NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001082924-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |