Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7125650 | 1.00 | DNM2 (0.33) | DNM2L3MBTL1MEN1ALDH1A1LMNA | |
| SCHEMBL7117880 | 1.00 | DNM2 (0.33) | DNM2L3MBTL1MEN1ALDH1A1LMNA | |
| SCHEMBL7115946 | 1.00 | DNM2 (0.33) | DNM2L3MBTL1MEN1ALDH1A1LMNA | |
| SCHEMBL7125112 | 1.00 | DNM2 (0.33) | DNM2L3MBTL1MEN1ALDH1A1LMNA | |
| SCHEMBL7128032 | 1.00 | DNM2 (0.33) | DNM2L3MBTL1MEN1ALDH1A1LMNA | |
| SCHEMBL7121610 | 1.00 | DNM2 (0.33) | DNM2L3MBTL1MEN1ALDH1A1LMNA | |
| SCHEMBL7122685 | 1.00 | DNM2 (0.33) | DNM2L3MBTL1MEN1ALDH1A1LMNA | |
| SCHEMBL7117869 | 1.00 | DNM2 (0.33) | DNM2L3MBTL1MEN1ALDH1A1LMNA | |
| SCHEMBL7121624 | 1.00 | DNM2 (0.33) | DNM2L3MBTL1MEN1ALDH1A1LMNA | |
| SCHEMBL7124374 | 1.00 | DNM2 (0.33) | DNM2L3MBTL1MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653317-B2 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | SOCIETE L'OREAL S.A. (FR) | 2003-11-25 | — | — | US | claimed |
| US-20030130294-A1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | MAHE YANN (FR) | 2003-07-10 | — | — | US | claimed |
| US-6455054-B2 | THERAPY FOR SKIN DISORDERS | SOCIETE L'OREAL S.A. (FR) | 2002-09-24 | — | — | US | claimed |
| US-20010051139-A1 | TREATING SKIN AFFLICTIONS/CONDITIONS WITH 2-AMINO-4-ALKYLAMINOPYRIMIDINE 3-OXIDE COMPOUNDS | SOCIETE L'OREAL S.A. (FR) | 2001-12-13 | — | — | US | claimed |
| US-20010044444-A1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | MAHE YANN (FR) | 2001-11-22 | — | — | US | claimed |
| US-6291468-B1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | SOCIETE L'OREAL S.A. (FR) | 2001-09-18 | — | — | US | claimed |
| US-6653317-B2 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | SOCIETE L'OREAL S.A. (FR) | 2003-11-25 | — | — | US | disclosed |
| US-20030130294-A1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | MAHE YANN (FR) | 2003-07-10 | — | — | US | disclosed |
| US-6511659-B2 | Treatment of alopecia, cosmetics | SOCIETE L'OREAL S.A. (FR) | 2003-01-28 | — | — | US | disclosed |
| US-6455054-B2 | THERAPY FOR SKIN DISORDERS | SOCIETE L'OREAL S.A. (FR) | 2002-09-24 | — | — | US | disclosed |
| US-20010051139-A1 | TREATING SKIN AFFLICTIONS/CONDITIONS WITH 2-AMINO-4-ALKYLAMINOPYRIMIDINE 3-OXIDE COMPOUNDS | SOCIETE L'OREAL S.A. (FR) | 2001-12-13 | — | — | US | disclosed |
| US-20010044444-A1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | MAHE YANN (FR) | 2001-11-22 | — | — | US | disclosed |
| US-6291468-B1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | SOCIETE L'OREAL S.A. (FR) | 2001-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010051139-A1 | TREATING SKIN AFFLICTIONS/CONDITIONS WITH 2-AMINO-4-ALKYLAMINOPYRIMIDINE 3-OXIDE COMPOUNDS | TPMT, IL33, PTGS2 | DNM2 4229/4885L3MBTL1 1287/4885MEN1 4519/4885 |
| US-20030130294-A1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | TK2, TYR, MTR | DNM2 3975/4885L3MBTL1 2325/4885MEN1 4382/4885 |
| US-20010044444-A1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | TK2, TYR, MTR | DNM2 3947/4885L3MBTL1 2387/4885MEN1 4366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.