Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17209569 | 0.89 | ALOX5 (0.48) | ALOX5ALDH1A1GAACYP2C9CYP1A2 | |
| SCHEMBL8961331 | 0.89 | ALOX5 (0.48) | ALOX5ALDH1A1GAACYP2C9CYP1A2 | |
| SCHEMBL8467415 | 0.89 | ALOX5 (0.48) | ALOX5ALDH1A1GAACYP2C9CYP1A2 | |
| SCHEMBL3716250 | 0.85 | ALDH1A1 (0.46) | ALOX5ALDH1A1GAACYP2C9CYP1A2 | |
| SCHEMBL2032763 | 0.84 | LMNA (0.40) | ALOX5ALDH1A1GAACYP2C9CYP1A2 | |
| SCHEMBL5932125 | 0.83 | ALDH1A1 (0.44) | ALOX5ALDH1A1GAACYP2C9CYP1A2 | |
| SCHEMBL7515731 | 0.83 | ALDH1A1 (0.44) | ALOX5ALDH1A1GAACYP2C9CYP1A2 | |
| SCHEMBL5932136 | 0.83 | ALDH1A1 (0.45) | ALOX5ALDH1A1GAACYP2C9CYP1A2 | |
| SCHEMBL5933190 | 0.82 | ALDH1A1 (0.43) | ALOX5ALDH1A1GAACYP2C9CYP1A2 | |
| SCHEMBL5655825 | 0.82 | ALDH1A1 (0.43) | ALOX5ALDH1A1GAACYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |